Abortive medications. The most successful treatments are Imitrex (sumatriptan) or other triptans, and breathing oxygen through a face mask for twenty minutes. Other options include: ergotamine drugs and intranasal lidocaine.
Preventive medications. Your doctor can prescribe preventive medications to shorten the length of the cluster headache period as well as decrease the severity of the headaches. All cluster headache sufferers should take preventive medication unless their cluster periods last less than two weeks. Some drugs used in the prevention of cluster headaches include verapamil, lithium, divalproex sodium, prednisone (only short courses), and ergotamine tartrate.
Surgery. This may be an option for people with chronic cluster headaches who have not been helped with standard therapy. Most of the procedures involve blocking the trigeminal nerve.
All of these treatments should be used under the direction of a doctor familiar with treating cluster headaches. As with any medication, it is important to carefully follow the label instructions and your doctor's advice.