Many drugs can induce acute headache, including nitroglycerin,
antihypertensive agents (beta blockers, calcium channel blockers,
angiotensin-converting enzyme [ACE] inhibitors, and methyldopa), dipyridamole,
hydralazine, sildenafil, histamine receptor antagonists (e.g., cimetidine and
ranitidine), NSAIDs (especially indomethacin), cyclosporine, and antibiotics
(especially amphotericin, griseofulvin, tetracycline, and sulfonamides).
Drug-induced aseptic meningitis, a rare occurrence, has numerous possible
causes, including NSAIDs, antibiotics (e.g., trimethoprim-sulfamethoxazole,
sulfasalazine, cephalosporins, ciprofloxacin, isoniazid, and penicillin),
intrathecal drugs and diagnostics (e.g., antineoplastic agents such as
methotrexate and cytarabine; gentamicin; corticosteroids; spinal anesthesia;
baclofen; repeated iophendylate for myelography; and radiolabeled albumin);
intraventricular chemotherapy; intravenous immunoglobulin; vaccines (polio;
measles, mumps, and rubella; and hepatitis B); and some other drugs, such as
carbamazepine, muromonab-CD3, and ranitidine.43
Since it is brief, the vision loss of ocular migraines is not usually treated. But you may need relief for the headache that accompanies or follows it.
The primary treatment for ocular migraines is to reduce exposure to triggers. Calcium-channel blockers are the main drug treatment for ocular migraines. They work by relaxing the blood vessels. One example is Cardene, which can be given as a pill or as a tab you put under the tongue.
The clinical presentation of drug-induced aseptic meningitis is the same as
that of viral meningitis. Cerebrospinal fluid findings are the same as those in
viral meningitis, except for a neutrophil predominance; however, in cases
induced by intravenous immunoglobulin, eosinophils are present.
WebMD Medical Reference from WebMD Scientific American Medicine