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Medication Headaches

Many drugs can induce acute headache, including nitroglycerin, antihypertensive agents (beta blockers, calcium channel blockers, angiotensin-converting enzyme [ACE] inhibitors, and methyldopa), dipyridamole, hydralazine, sildenafil, histamine receptor antagonists (e.g., cimetidine and ranitidine), NSAIDs (especially indomethacin), cyclosporine, and antibiotics (especially amphotericin, griseofulvin, tetracycline, and sulfonamides).

Drug-induced aseptic meningitis, a rare occurrence, has numerous possible causes, including NSAIDs, antibiotics (e.g., trimethoprim-sulfamethoxazole, sulfasalazine, cephalosporins, ciprofloxacin, isoniazid, and penicillin), intrathecal drugs and diagnostics (e.g., antineoplastic agents such as methotrexate and cytarabine; gentamicin; corticosteroids; spinal anesthesia; baclofen; repeated iophendylate for myelography; and radiolabeled albumin); intraventricular chemotherapy; intravenous immunoglobulin; vaccines (polio; measles, mumps, and rubella; and hepatitis B); and some other drugs, such as carbamazepine, muromonab-CD3, and ranitidine.43

Recommended Related to Migraines/Headaches

Ocular Migraine Symptoms and Diagnosis

In 50% of cases, ocular migraines cause temporary and dramatic visual disturbance. In the other half of cases, ocular migraines can cause lesser vision disturbances such as: Blurring Partial vision loss Scotomas, or a blank spots in your vision Dimming Flashes of light Ocular migraines are usually brief, lasting less than five minutes. However, they can last up to 30 minutes. Forty-one percent of people have a headache during the vision loss. Twenty-five percent have it before...

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The clinical presentation of drug-induced aseptic meningitis is the same as that of viral meningitis. Cerebrospinal fluid findings are the same as those in viral meningitis, except for a neutrophil predominance; however, in cases induced by intravenous immunoglobulin, eosinophils are present.

WebMD Medical Reference from WebMD Scientific American Medicine

Reviewed by Lily Jung, MD on December 01, 2006
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