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How to Get Past Tension Headaches

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May 1, 2001 -- Since headaches affect so many of us, we may just write them off as an unpleasant fact of life. Long-term, persistent tension headaches occur about every other day in 3% of women -- and in about half as many men -- and they interfere with work in almost half of sufferers.

The best shot at knocking out these tenacious headaches, according to a new study, is with a combination of antidepressants and stress-management therapy. This two-sided attack works better than either treatment alone, say researchers.

The study appears in the May 2 issue of TheJournal of the American Medical Association.

Do you have tension headaches or migraines? WebMD has a place to talk about it: Migraines: Open Discussion.

"Lots of people with [recurrent] headaches may have tried treatment that didn't work, so now they're not seeking treatment anymore," says researcher Kenneth A. Holroyd, PhD, a professor of psychology at Ohio University in Athens. "Our study suggests that they shouldn't give up -- this combination improves the quality of life for many."

And the use of antidepressants doesn't indicate that doctors think the headaches are a symptom of the blues.

"Just because headache patients are given antidepressants doesn't mean that they're depressed," Lawrence C. Newman, MD, tells WebMD after reviewing the findings. These medications relieve pain apart from any effect on depression, explains Newman, director of the Headache Institute at St. Luke's-Roosevelt Hospital in New York.

Holroyd's team studied more than 200 adults with tension headaches occurring 26 days a month, on average. About three-quarters of the people studied were women, and about half had not seen a doctor in at least six months, despite their history of persistent headaches.

Subjects were placed in one of four groups: one that got an antidepressant medication; another that got an inactive placebo medication; a third that got stress management therapy and placebo; and a fourth that got stress management and an antidepressant medication. The antidepressants used were from an older group of drugs known as tricyclic antidepressants.

Although antidepressants and stress management were each better than placebo in reducing headaches, the number of painkillers taken, and interference with work, the antidepressants worked faster. With combined therapy, 64% of the study volunteers had less than half the number of headaches, compared with 38% of the people on antidepressants alone, 35% of those on stress management alone, and 29% of those on the inactive placebo.

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