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    Colic May Be Linked to Childhood Migraine

    Expert suspects disrupted sleep cycles might play a role in both disorders

    continued...

    The researchers found that nearly 73 percent of children who had migraines also had colic as babies, while just 26.5 percent of those without migraine reported colic. Slightly more children who had migraine without aura (without visual and other sensory disturbances) reported having had colic than those who had migraine with aura. Overall, the odds that someone with a migraine had colic as a child were 6.6 times higher than the odds they didn't have colic, the study found.

    The researchers didn't find an association between tension-type headaches and colic.

    The mechanism behind the colic-migraine association isn't clear, and the authors say more research is needed to understand the connection. But Titomanlio said it could be that nerve terminals in the brain and in the gut may be overly sensitized, leading to pain in the head or the gut.

    Dr. Phyllis Zee, professor of neurology and director of the sleep disorders center at the Feinberg School of Medicine at Northwestern University in Chicago, said this is the largest study to date showing "a strong association between infantile colic and migraine." But, she added, this study only found an association; it doesn't prove that one disorder causes the other.

    Zee, the author of an accompanying journal editorial, suspects disrupted sleep cycles may play a role in both disorders, along with disruption in melatonin, a hormone that induces sleep and regulates the body's internal time clock. While most melatonin is made in the brain, Zee said that some is made by cells in the digestive tract. And the release of melatonin in the digestive system can affect the motility of the intestines, which could theoretically cause some colic symptoms.

    "Sleep and circadian rhythm disruptions may be a prominent trigger in colic and in migraine," she said.

    Zee said if a melatonin or sleep-wake cycle disturbance is to blame, parents can take steps to change these factors without drugs.

    "Don't get too much light at night. Try to get more light during the day. Take the baby outside during the day, and at night, have a sleep environment that's darker," she suggested.

    If your baby's colicky time is at night, try to avoid bright lights or stimulating sounds, such as from the TV. And don't bounce the baby around too much, she said.

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