Other antidepressants may be tried if you do not respond well to amitriptyline or nortriptyline. The choice of antidepressant to treat your migraines may depend on your ability to tolerate the side effects of the medicine.
Side effects of tricyclic antidepressants include:
Never suddenly stop taking antidepressants. The use of any antidepressant should be tapered off slowly and only under the supervision of a doctor. Abruptly stopping antidepressant medicine can cause negative side effects or a relapse into a depressive episode or panic disorder.
FDA advisories. The U.S. Food and Drug Administration (FDA) has issued:
A warning about taking triptans, used for headaches, with SSRIs (selective serotonin reuptake inhibitors) or SNRIs (selective serotonin/norepinephrine reuptake inhibitors). Taking these medicines together can cause a very rare but serious condition called serotonin syndrome.
In this article
WebMD Medical Reference from Healthwise
April 17, 2014
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