Midrin is a combination of the drugs isometheptene, acetaminophen,
and dichloralphenazone. This drug combines properties of a pain reliever, a
medicine that helps narrow (constrict) blood vessels, and a mild sedative to
In some people, certain foods and drinks -- or components they contain -- can trigger a migraine. One well-accepted migraine trigger is tyramine.
Tyramine is a substance found naturally in some foods. It's especially found in aged and fermented foods, such as:
Some types of beer
Also, foods high in protein may contain more tyramine if:
They have been stored for a long time
They have not been kept cold enough
Midrin is a prescription medicine that comes in tablet form. The
usual adult dosage is 2 tablets taken together followed by 1 tablet every hour
until your pain is relieved. You should not take more than 5 tablets within a
You may not be able to use Midrin if you have glaucoma, renal
disease, hypertension, certain heart problems, hepatic disease, or if you are
taking a monoamine oxidase inhibitor (MAOI). Before you take this medicine, be sure to discuss with your
doctor whether Midrin is right for you.