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    Is Your MS Treatment Working?


    WebMD Feature
    Reviewed by Neil Lava, MD

    Multiple sclerosis (MS) is a complex, individual disease. No two people with this disease have the same symptoms, progression, or response to treatment. That makes a collaborative approach with your doctor even more important than usual. It's key to tailoring multiple sclerosis treatment just for you, and it's especially helpful if you need to make changes to your MS treatment along the way.

    "Become empowered to participate in your treatment decisions," says Barbara S. Giesser, MD, clinical director of the UCLA MS Program at the David Geffen School of Medicine in Los Angeles. "It's the single most important underlying principle, especially for a chronic, unpredictable condition such as MS."

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    People with secondary progressive multiple sclerosis (SPMS) start out with another type of MS -- relapsing-remitting multiple sclerosis. If you've been diagnosed with SPMS you may have had relapsing-remitting MS for a decade or more. That's when you may begin to feel a shift in your disease. The changes are often not easy to recognize. But you may notice that your relapses may not seem to fully go away. Most people with relapsing-remitting MS -- about 80% -- eventually get secondary progressive...

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    How do you do that? By seeking information from reputable sources and communicating well with your health care providers.

    When MS Treatment Isn't Working

    Before you and your doctor take any steps to switch treatment, make sure you're taking your MS medication exactly as prescribed. "One of the most common causes of a poor response is simply not taking medications the right way," says Jack S. Burks, MD, chief medical officer of the Multiple Sclerosis Association of America.

    Whatever you do, don't just stop taking medications because you think they're not working -- or because you think you don't need them. Talk with your doctor about your concerns. Burks' patients sometimes say, "Gee, doc, I haven't had an attack in a long time, maybe I don't need these medications," to which he responds, "Maybe the reason you haven't had an attack is because you've been taking the medicine!"

    Each class of MS medication works in different ways. So be clear about what your MS medication is designed to do before deciding that it's not working. For example, disease modifying therapies (DMTs) slow MS progression. If you're also expecting them to control all your symptoms, says Giesser, you may be alarmed if that doesn't happen.

    Burks recommends starting with a basic question like this: "Given my situation, doctor, how do you decide whether or not my medication is working up to expectations?" Although a tall order, the best way is by looking at a wide range of factors from symptoms and function to number of attacks and MRI findings.

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