Skip to content

Multiple Sclerosis Health Center

Select An Article

Multiple Sclerosis and Novantrone Therapy

Font Size

Novantrone is a drug that works by suppressing the immune system to lessen its attack on the myelin sheath that surrounds nerves. It can slow increases in disability and reduce the relapse rate in people with worsening forms of relapsing-remitting, progressive-relapsing, and secondary-progressive MS.

Novantrone also reduces the number of new lesions in the brain as seen on MRI.

Recommended Related to Multiple Sclerosis

What to Expect With Primary Progressive MS

For Mimi Mosher, a person with primary progressive MS, clarity first came when she lost her vision. Her eyesight steadily eroded by multiple sclerosis, Mimi now lived in a near-constant dusk. The realization came at a scary time. “I was driving. I thought, I can’t do this anymore. I had to pull off the road and let my friend drive,” says Mimi. Until then, Mimi had been living “in a deep state of denial” about her advancing symptoms. As her primary progressive MS forced her to hand over her car...

Read the What to Expect With Primary Progressive MS article > >

How Is Novantrone Given for Multiple Sclerosis?

Novantrone is administered directly into a vein through an intravenous (IV) drip. The treatment may take place at a treatment center every three months.

What Happens Before Treatment With Novantrone?

Before Novantrone treatment begins, the following tests will be given:

  • Blood tests (blood cell counts and liver function tests).
  • Electrocardiogram (EKG or ECG).
  • Echocardiogram heart test (to determine the strength of your heart muscle).
  • Height and weight.
  • Education session. You will learn about pre-treatment and post-treatment medication to control nausea, when to get blood tests, and continuing treatment.

What Should my Doctor Know Before I Start Novantrone?

Before starting Novantrone, tell your doctor if you have any of the following conditions:

  • Dental disease
  • Gout
  • Heart disease*
  • Infection (especially a viral infection such as chicken pox or herpes)
  • Liver disease
  • Recent radiation therapy*
  • Allergies
  • Pregnant or trying to get pregnant
  • Breastfeeding
  • Unusual or unexpected bleeding
  • Have received chemotherapy*

Your neurologist will discuss the potential benefits and risks of Novantrone with you and your family. If you have any concerns or questions, discuss them with your doctor.

* Patients who have or have had heart disease or cancer treatment should not take Novantrone. Serious side affects could result. Your doctor should thoroughly check for warning signs before beginning your treatment with Novantrone.

What Can I Expect During Novantrone Treatment?

Plan to be at the treatment center about two hours to get Novantrone. During this time you will be given the drug through an IV drip. Wear comfortable, warm clothes.

Your nurse will check your blood pressure, pulse, and weight before treatment and will review your pre-treatment test results.

Bring something to occupy your time, such as a book.

Next Article:

Today on WebMD

nerve damage
Learn how this disease affects the nervous system.
woman applying lotion
Ideas on how to boost your mood and self-esteem.
 
woman pondering
Get personalized treatment options.
man with hand over eye
Be on the lookout for these symptoms.
 
brain scan
ARTICLE
worried woman
ARTICLE
 
neural fiber
ARTICLE
white blood cells
VIDEO
 
sunlight in hands
ARTICLE
illustration of human spine
ARTICLE
 
muscle spasm
ARTICLE
green eyed woman with glasses
ARTICLE
 

WebMD Special Sections