Novantrone is a drug that works by suppressing the immune system to lessen its attack on the myelin sheath that surrounds nerves. It can slow increases in disability and reduce the relapse rate in people with worsening forms of relapsing-remitting, progressive-relapsing, and secondary-progressive MS.
Novantrone also reduces the number of new lesions in the brain as seen on MRI.
If you have progressive relapsing multiple sclerosis (PRMS), you’ll have distinct attacks of symptoms, called relapses. You may or may not fully recover after these flares. Between relapses, the disease continues to get worse slowly.
PRMS is the least common type of multiple sclerosis. It affects about 5% of people with the condition.
You may not be able to reverse the disease, but there are treatments that can ease your symptoms and make your relapses less severe and happen less often.
Your neurologist will discuss the potential benefits and risks of Novantrone with you and your family. If you have any concerns or questions, discuss them with your doctor.
* Patients who have or have had heart disease or cancer treatment should not take Novantrone. Serious side affects could result. Your doctor should thoroughly check for warning signs before beginning your treatment with Novantrone.
What Can I Expect During Novantrone Treatment?
Plan to be at the treatment center about two hours to get Novantrone. During this time you will be given the drug through an IV drip. Wear comfortable, warm clothes.
Your nurse will check your blood pressure, pulse, and weight before treatment and will review your pre-treatment test results.
Bring something to occupy your time, such as a book.