Novantrone is a drug that works by suppressing the immune system to lessen its attack on the myelin sheath that surrounds nerves. It can slow increases in disability and reduce the relapse rate in people with worsening forms of relapsing-remitting, progressive-relapsing, and secondary-progressive MS.
Novantrone also reduces the number of new lesions in the brain as seen on MRI.
Although multiple sclerosis (MS) occurs most commonly in adults, it is increasingly being diagnosed in children and teenagers. Of the 400,000 diagnosed cases of MS in the U.S., 8,000 to 10,000 are in children up to 18 years old. Neurologists think there are probably many more children with MS that have not been diagnosed.
Education session. You will learn about pre-treatment and post-treatment medication to control nausea, when to get blood tests, and continuing treatment.
What Should my Doctor Know Before I Start Novantrone?
Before starting Novantrone, tell your doctor if you have any of the following conditions:
Infection (especially a viral infection such as chicken pox or herpes)
Recent radiation therapy*
Pregnant or trying to get pregnant
Unusual or unexpected bleeding
Have received chemotherapy*
Your neurologist will discuss the potential benefits and risks of Novantrone with you and your family. If you have any concerns or questions, discuss them with your doctor.
* Patients who have or have had heart disease or cancer treatment should not take Novantrone. Serious side affects could result. Your doctor should thoroughly check for warning signs before beginning your treatment with Novantrone.
What Can I Expect During Novantrone Treatment?
Plan to be at the treatment center about two hours to get Novantrone. During this time you will be given the drug through an IV drip. Wear comfortable, warm clothes.
Your nurse will check your blood pressure, pulse, and weight before treatment and will review your pre-treatment test results.
Bring something to occupy your time, such as a book.