During clinical trials, people who have multiple sclerosis (MS) participate in studies that test new therapies for the disease. The therapies tested in clinical trials have shown promise in laboratory and animal research, but they may not have been shown to be safe and effective for humans yet. Each trial requires that a person meet specific requirements (involving, for example, age, time since diagnosis, and course of MS) in order to ensure that the results will be clear enough to be useful.Medicines being tested in clinical trials pass through four phases:Phase I: Testing for safetyPhase II: Testing for effectiveness against the disease. This phase is usually limited to less than 50 people.Phase III: Comparing the medicine with a placebo or an already approved therapy. Participants are watched closely for side effects. This phase may involve hundreds of people in several locations.Phase IV: Further testing of approved medicinesCall the National Multiple Sclerosis Society
Exercise is an important part of home treatment for people who have multiple sclerosis (MS). It has benefits in both early and advanced stages of the disease. Regular exercise can help you: Maintain muscle strength and improve coordination.Maintain and increase endurance.Improve flexibility and range of limb motion.Improve cardiovascular fitness. Prevent pressure sores.Control weight.Reduce the likelihood of becoming constipated.Exercise can also promote a sense of well-being and improve your mood.A physical therapist can help you learn exercises and stretches to do at home to improve posture, strength, flexibility, and endurance. A physical or occupational therapist can also help you to:Plan more efficient movements for daily living activities (such as bathing and dressing) so that these activities are easier and less tiring. Improve balance and walking. Use walking aids (such as canes or walkers) correctly.There are also seated exercises for the person who cannot walk but can move
Total lymphoid irradiation uses radiation to limit the production of white blood cells (lymphocytes). These cells help the body's immune system destroy foreign cells and fight infection. The treatment was first developed to treat Hodgkin's lymphoma, a form of cancer.In theory, total lymphoid irradiation may help prevent progression of multiple sclerosis (MS) by limiting the production of lymphocytes and thus limiting the activity of the immune system. The results of studies done so far have failed to show any benefit.Total lymphoid irradiation remains an experimental treatment for MS. The treatment may be toxic and potentially dangerous and typically is not recommended.Side effects of this treatment may include:Absence of menstrual periods in women.Nausea.Fatigue.Depression.Minor bone fractures.Impaired immune system.