Progeria, also known as Hutchinson-Gilford progeria syndrome (HGPS), is a rare genetic condition that causes a child's body to grow old quickly. There's no cure, but treatment can ease or delay symptoms.
Clubbed nails. Increased curvature of the nail plate may be due to a wide variety of causes. In this patient, the large, convex nails are a hereditary anomaly and were found to be present in both father and brother. Other causes of clubbing of the nails in children include cyanotic congenital heart disease, cystic fibrosis, and chronic inflammatory bowel disease.