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How Well Are You Managing MS?

Answer a few questions, and you'll get:

  • Treatment options for your type of MS
  • Information about the progression of the disease
  • Tips for dealing with symptoms while still enjoying life

Reviewed by Neil Lava, MD on March 19, 2015


National MS Society: "Expert Opinion Paper: Management of MS Related," "Exercise as Part of Everyday Life," "Exercise," "Stress," "Pregnancy and Reproductive Issues," Optic Neuritis," "Clinically isolated syndrome (CIS), "Adherence. Starting a Disease-Modifying Therapy and Sticking with It," "Talking about Initiating and Adhering to Treatment with Injectable Disease-Modifying Agents," "The MS Disease-Modifying Medications," "Emotional Changes," “FDA Approves Plegridy (Pegylated Interferon Beta) For Relapsing MS.”

Multiple Sclerosis International Federation: "World of MS - Resources - Clinically isolated syndrome."

McDonald, W. I. Annals of Neurology, 2001.

Gold, R. Therapeutic Advances in Neurological Disorders, 2010.

National Institute of Neurological Disorders and Stroke (NINDS): "Multiple Sclerosis: Hope Through Research."

Kachuck, N. "Monitoring Disease Progression: Incorporating MRI and New Modalities in Clinical Decision Making" (n.d.).

Kalb, P. Multiple sclerosis: The questions you have, the answers you need, Demos Health, 2008.

Crayton, H. Neurology, 2004.

Rae-Grant, A. D. Multiple Sclerosis, 1999.

Dean, L. PubMed Health, 2011.

NAAC National Anemia Action Council: "Anemia FAQs of Symptoms, Causes, Diagnosis and Treatment."

U.S. Food and Drug Administration.

U.S. National Library of Medicine: "Multiple Sclerosis."

Havrdova, E. Multiple Sclerosis, 2009.

MedlinePlus: "Drugs, Herbs and Supplements."

Frohman, E. Clinical Neuropharmacology, 2004.

Cleveland Clinic: "Mycophenolate Mofetil (CellCept)."

Goodin, D.S. Neurology, 2003.

Marrie, R.A. Neurology, 2010.

Hasson, J. "Is there an MS diet?" Momentum, National MS Society, Fall 2008.

Nowack, D. "Is there a diet that helps people with MS?" Momentum, National MS Society, Fall 2008.

Schwarz, S. Multiple Sclerosis, 2005.

Bowling, A. InsideMS, November 2006.

Munger, K. Neurology, Jan 13, 2004.

Brown, T. Physical Medicine and Rehabilitation Clinics of North America, May 2005.

National Center of Physical Activity and Disability: "Disability/Condition: Multiple Sclerosis: Designing an Exercise Program."

Solaro, C. Neurology, 2004.

Moulin, D.E. Neurology, 1988.

Miller, D. Lancet Neurology, 2005.

FDA News Release

Beck, R.W. New England Journal of Medicine, 1992.

The Multiple Sclerosis Study Group. Annals of Neurology, 1990.

Rudge, P. Journal of Neurology, Neurosurgery & Psychiatry, 1989.

Symister, P. Health Psychology, 2003.

Chang, E., ed. Optimism & Pessimism: Implications for Theory, Research, and Practice, American Psychological Association, 2001.

Koch, M. Epilepsia, 2008.

Attarian, H.P. Archives of Neurology, 2004.

Office of Dietary Supplements: "Dietary Supplement Fact Sheet: Vitamin D."

Pierrot-Deseilligny, C. Journal of Neurology, 2009.

Mohr, D. British Medical Journal, 2004.

Gray, O. Cochrane Database of Systematic Reviews, 2004.

Goodkin, D.E. Annals of Neurology, 1995.

Calabresi, P.A. Neurology, 2002.

Cohen. Neurology, Feb 10, 2009.

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Rebif (interferon beta-1a) is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS.


Before beginning treatment, you should discuss the potential benefits and risks associated with Rebif with your healthcare provider.

Rebif can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking Rebif.

  • Behavioral health problems including depression and suicidal thoughts. You may have mood problems including depression (feeling hopeless or feeling bad about yourself), and thoughts of hurting yourself or suicide
  • Liver problems or worsening of liver problems including liver failure. Symptoms may include nausea, loss of appetite, tiredness, dark colored urine and pale stools, yellowing of your skin or the white part of your eye, bleeding more easily than normal, confusion, and sleepiness. During your treatment with Rebif you will need to see your healthcare provider regularly and have regular blood tests to check for side effects
  • Serious allergic and skin reactions. Symptoms may include itching, swelling of your face, eyes, lips, tongue or throat, trouble breathing, anxiousness, feeling faint, skin rash, hives, sores in your mouth, or skin blisters and peels
  • Injection site problems. Symptoms at the injection site may include redness, pain, swelling, color changes (blue or black), and drainage of fluid.
  • Blood problems. Rebif can affect your bone marrow and cause low red and white blood cell, and platelet counts. In some people, these blood cell counts may fall to dangerously low levels. If your blood cell counts become very low, you can get infections and problems with bleeding and bruising. Your healthcare provider may ask you to have regular blood tests to check for blood problems
  • Seizures. Some people have had seizures while taking Rebif

Rebif will not cure your MS but may decrease the number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common in people with MS.

Do not take Rebif if you are allergic to interferon beta, human albumin, or any of the ingredients in Rebif.

Before you take Rebif, tell your healthcare provider if you have or have had any of the following conditions:

  • mental illness, including depression and suicidal behavior
  • liver problems, bleeding problems or blood clots, low blood cell counts, seizures (epilepsy), or thyroid problems
  • drink alcohol
  • you are pregnant or plan to become pregnant. It is not known if Rebif will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with Rebif.
  • you are breastfeeding or plan to breastfeed. It is not known if Rebif passes into your breast milk. You and your healthcare provider should decide if you will use Rebif or breastfeed. You should not do both.

Tell your healthcare provider about all medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

The most common side effects of Rebif include:

  • flu-like symptoms. You may have flu-like symptoms when you first start taking Rebif. You may be able to manage these flu-like symptoms by taking over-the-counter pain and fever reducers. For many people, these symptoms lessen or go away over time. Symptoms may include muscle aches, fever, tiredness, and chills
  • stomach pain
  • change in liver blood tests

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Rebif. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call

Please see Rebif Prescribing Information and Medication Guide.