Skip to content

    Multiple Sclerosis Health Center

    Font Size
    A
    A
    A

    Antibody May Help Heal MS Nerve Damage

    Antibody Treatment Shows Promise in Preliminary Lab Tests on Mice
    By
    WebMD Health News
    Reviewed by Louise Chang, MD

    Oct. 9, 2007 -- Scientists may have found a way to reverse some nerve damage from multiple sclerosis -- a discovery that may lead to new treatments for MS.

    Researchers today reported that they've successfully used an antibody to restore nerves' fatty sheath (called myelin) that had been ravaged by MS in mice.

    The scientists, who work at the Mayo Clinic College of Medicine in Rochester, Minn., haven't tried that technique yet in people.

    The Mayo Clinic's Arthur Warrington, PhD, and colleagues tested a lab-made antibody called rHIgM22.

    They injected the antibody into mice with an MS-like condition that destroyed the mice's myelin.

    A single dose of the antibody helped repair the mice's myelin within five weeks.

    The "stage is set" for myelin repair, but MS prevents that repair from happening, write Warrington and colleagues. They suggest that rHIgM22 antibody treatment might allow that repair to take place.

    The findings were presented today in Washington at the American Neurological Association's annual meeting.

    Today on WebMD

    nerve damage
    Learn how this disease affects the nervous system.
    woman applying lotion
    Ideas on how to boost your mood and self-esteem.
     
    woman pondering
    Get personalized treatment options.
    man with hand over eye
    Be on the lookout for these symptoms.
     
    brain scan
    ARTICLE
    worried woman
    ARTICLE
     
    neural fiber
    ARTICLE
    white blood cells
    VIDEO
     
    sunlight in hands
    ARTICLE
    marijuana plant
    ARTICLE
     
    muscle spasm
    ARTICLE
    Neuron
    ARTICLE