MS That Runs in Families May Be Worse
Brain Damage From Multiple Sclerosis May Be More Severe in Patients With Family History of MS
Oct. 12, 2007 -- Multiple sclerosis may cause more severe brain damage in
patients who have a relative who had multiple sclerosis.
Researchers reported that news today in Prague, Czech Republic, at the 23rd
Congress of the European Committee for Treatment and Research in Multiple
The scientists -- who work at the State University of New York at Buffalo --
included Robert Zivadinov, MD, PhD.
They studied 759 MS patients, 26% of whom had a relative with multiple
sclerosis. The patients got brain scans using magnetic resonance imaging
Zivadinov and colleagues analyzed the patients' brain scans. The scientists
noticed more severe brain damage in the brain scans of patients with a family
history of MS, compared with those with no relatives with MS.
That pattern was stronger for MS patients with a parent or sibling who had
MS, compared with patients who had a more distant relative with MS.
However, family history of multiple sclerosis wasn't linked to the degree of
disability due to MS, the length of time the patients had had MS, or how their
MS had progressed.
"This warrants further investigation," write Zivadinov and