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Multiple Sclerosis: Pain Medicines - Topic Overview

Pain is a frequent problem for people who have multiple sclerosis (MS). Medicines that may be used to bring relief include:

  • Nonprescription pain relievers. These include acetaminophen (such as Tylenol), ibuprofen (such as Advil), and naproxen (such as Aleve). Be safe with medicines. Read and follow all instructions on the label.
  • Amitriptyline, imipramine (Tofranil), or nortriptyline (Pamelor), for burning sensations.
  • Carbamazepine (Tegretol).
  • Gabapentin (Neurontin). This drug may also help relieve muscle stiffness and tightness (spasticity).
  • Phenytoin (Dilantin).
  • Pregabalin (Lyrica).

Some forms of natural or man-made substances related to marijuana, called cannabinoids, may help relieve pain.

Recommended Related to Multiple Sclerosis

Can Medical Marijuana Treat Multiple Sclerosis?

If you live in a state where it's legal and your doctor OKs it, medical marijuana might be an option to help treat some of your MS symptoms. Your doctor isn't likely to suggest you use it until you try other medicines first. He might recommend it if the treatments you take now aren't working.

Read the Can Medical Marijuana Treat Multiple Sclerosis? article > >

Pain that does not respond to these medicines can sometimes be treated with an injection of long-acting anesthetic.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: May 22, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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