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Multiple Sclerosis: Total Lymphoid Irradiation - Topic Overview

Total lymphoid irradiation uses radiation to limit the production of white blood cells (lymphocytes). These cells help the body's immune system destroy foreign cells and fight infection. The treatment was first developed to treat Hodgkin's lymphoma, a form of cancer.

In theory, total lymphoid irradiation may help prevent progression of multiple sclerosis (MS) by limiting the production of lymphocytes and thus limiting the activity of the immune system. The results of studies done so far have failed to show any benefit.

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Relapsing-Remitting Multiple Sclerosis

Most people who have been diagnosed with multiple sclerosis (MS) have a type called relapsing-remitting MS (RRMS). It usually develops when you're in your 20s or 30s. If you have RRMS, you may have attacks when symptoms flare up. These are called relapses. A relapse is followed by recovery or remission of symptoms. A remission can last weeks, months, or even longer. When you are in remission, you may have few or no symptoms. The disease is stable during this time -- meaning it doesn't progress...

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Total lymphoid irradiation remains an experimental treatment for MS. The treatment may be toxic and potentially dangerous and typically is not recommended.

Side effects of this treatment may include:

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: February 15, 2012
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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