Total lymphoid irradiation uses radiation to limit the production of
white blood cells (lymphocytes). These cells help the
body's immune system destroy foreign cells and fight infection. The treatment
was first developed to treat
Hodgkin's lymphoma, a form of cancer, and has been
used successfully to treat people with
rheumatoid arthritis, which, like
multiple sclerosis (MS), is an
In theory, total lymphoid irradiation may help prevent progression of
MS by limiting the production of lymphocytes and thus limiting the activity of
the immune system. The results of studies done so far have failed to show any
Multiple sclerosis (MS) is a chronic and often disabling disease of the central nervous system, which consists of the brain, spinal cord, and optic nerves. The disease damages myelin, a fatty substance that normally surrounds and protects the nerves. It can also damage the nerves (called axons) within the central nervous system.
Results of this damage can range from mild (numbness in the limbs) to severe (paralysis or vision loss). About half of people with MS experience problems with concentration,...