Is Dengue Fever on the Rise in the U.S.?
WebMD News Archive
This laboratory-based active surveillance study was implemented in Florida
for a year starting in April of 1997. Sixty-seven county health department
epidemiologists were mailed information explaining the program and requesting
participation; the dengue case definition, specimen requirements, and transport
instructions were provided. Departments were instructed to distribute enclosed
materials to clinics, hospital ERs, health departments, and infectious disease
physicians. Samples were tested, and those found to be in the acute phase of
the disease were sent to the CDC for further analysis.
In Florida, 83 suspected dengue cases were analyzed. Of these cases, recent
dengue infection was detected in 22%. Of the cases studied, all four dengue
types were identified. In 29% of the suspected cases, dengue was ruled out, and
in 49% of the cases, a diagnosis was indeterminable due to inadequate blood
In the confirmed cases of dengue, 56% were second infections, 11% were the
person's first infection, and the remainder were indeterminable due to a lack
of necessary laboratory tests. Of the confirmed cases, 39% had hemorrhagic
manifestations. Also, of the confirmed cases, all had traveled from countries
within 10 days of the onset of illness: six patients had traveled from Haiti,
three from Puerto Rico, two from Columbia, two from Venezuela, one from
Barbados, one from Nicaragua, and one from Thailand.
Usually, the viremic period -- time that the virus circulates in the blood
stream -- is only four days, according to Gill. "One of the theories has
been that it would be very difficult to import the disease and have local
mosquitoes pick it up and start local transmission because the viremic period
was so short," she says. "The theory was that, by the time people
traveled back into the state, perhaps they would not be viremic anymore. But we
were able to isolate virus from individuals while they were in the state of
Florida, and that demonstrates that the risk of future transmission is
Is it possible that dengue fever will start to spread within Florida and to
other states? Yes, says Gill. "The last time dengue was ... [a problem] in
Florida was in the 1930s," she says. "There were big outbreaks in Tampa
and Miami. There hasn't been any local transmission documented since then.
[But,] certainly, individuals and mosquitoes that could be infected are coming
in and out of the state regularly. The incidence of dengue in the surrounding
countries is increasing dramatically."