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Rabies Can Spread Via Organ Transplants

Rare Case Led to 4 Deaths in Recipients Last Year
WebMD Health News

March 16, 2005 -- RabiesRabies occurs rarely among people, but it can spread through organ transplants from infected donors, says a new study.

Last year, four people died after receiving rabies-tainted organs or tissue from one donor, says the study. Doctors didn't know that the donor had rabies, probably from a bat bite. The organ donor had been healthy before having a stroke that led to his death.

"As organ and tissue transplantation becomes more common, the potential risks of disease transmission may increase," write the researchers. West Nile virus can also be spread through infected organs, they say. After a Transplant: What to Expect, How to Cope After a Transplant: What to Expect, How to Cope

Doctors should be aware of that and report any unusual outcomes in transplant recipients, says the study. Better national record keeping of such problems -- along with donors' autopsy reports, materials, and archived tissue samples -- could also help, write the researchers.

Few People Get Rabies

The four rabies cases unfolded in Texas in 2004. Rabies is extremely rare among people in the U.S. Only two cases were reported in 2003 and no more than six cases per year have been noted in the last decade, says the study.

However, the rabies virus is still present in some animals. Mainly wildlife -- bats, raccoons, foxes, skunks, and coyotes -- carry it in America. Pets are usually protected by rabies vaccines.

People can get rabies by being bitten by an infected animal. If there's any chance of rabies exposure, immediately clean the bite wound with soap and water and call a doctor. If rabies exposure is confirmed, a rabies vaccine can be given as a series of shots.

Had the Texas organ donor followed those steps last year, it might have saved lives.

As far as doctors knew at the time, he died of a brain hemorrhage. One person got his liver, two others each got a kidney, and a fourth got a blood vessel graft from the man after he died.

All four recipients showed signs of rabies within 30 days of their operation. They rapidly became sick, fell into a coma, and died with 50 days after their transplant.

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