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Germ-Infected Mosquitoes Can't Spread Dengue

Release of Bacteria-Carrying Mosquitoes Could Halt Dengue Spread

Residents' Decision: Release Mosquitoes or Risk Dengue continued...

The plan worked. Nearly 100% of mosquitoes in Yorkey's Knob and over 80% of mosquitoes in Gordonvale became infected with the dengue-inhibiting bacteria.

"Once releases ended, wolbachia continued to increase, until by the end of the wet season we had almost complete penetration," O'Neill said. "We expect these regions should have a much reduced risk of dengue transmission within them."

That remains to be seen. But if it holds true, the researchers already are making plans for regions with year-round dengue transmission.

"We want to conduct large field trials and are looking for approval in Thailand, Vietnam, Indonesia, and Brazil," O'Neill said.

If it works, mosquito releases won't have to continue indefinitely.

"The really interesting thing about wolbachia is it is potentially a one-off intervention and should be able to maintain itself in the mosquito population," O'Neill said. "We expect it to persist and offer control of dengue after a single intervention."

O'Neill and colleagues report their findings in two papers published in the Aug. 25 issue of the journal Nature.

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