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FDA to Limit Use of Antibiotics in Farm Animals

Move should help reduce threat of antibiotic resistance in human disease, agency says

WebMD News from HealthDay

Findings raise concerns about U.S. livestock

By Steven Reinberg

HealthDay Reporter

WEDNESDAY, Dec. 11 (HealthDay News) -- As experts continue to sound alarm bells about the rising resistance of microbes to antibiotics used by humans, the U.S. Food and Drug Administration on Wednesday announced it was curbing the use of the drugs in livestock nationwide.

"FDA is issuing a plan today, in collaboration with the animal health industry, to phase out the use of medically important [for treating human infections] antimicrobials in food animals for production purposes, such as to enhance growth rates and improve feeding efficiency," Michael Taylor, deputy commissioner for foods and veterinary medicine at the agency, said during a Wednesday morning press briefing.

Experts have long stressed that the overuse of antibiotics by the meat and poultry industry gives dangerous germs such as Staphylococcus and C. difficile a prime breeding ground to develop mutations around drugs often used by humans. But for years, millions of doses of antibiotics have been added to the feed or water of cattle, poultry, hogs and other animals to produce fatter animals while using less feed.

To try and limit this overuse, the FDA is asking pharmaceutical companies that make antibiotics for the farming industry to change the labels on their products to limit the use of these drugs to medical purposes only.

At the same time, the agency will be phasing in broader oversight by veterinarians to insure that the antibiotics are used only to treat and prevent illness in animals and not to enhance growth, he said.

"What is voluntary is only the participation of animal pharmaceutical companies. Once these labeling changes have been made, these products will only be able to be used for therapeutic reasons with veterinary oversight," Taylor explained.

"With these changes, there will be fewer approved uses [of these drugs] and remaining uses will be under tighter control," Taylor said.

The most common antibiotics used in feed and also prescribed for humans affected by the new rule include tetracycline, penicillin and the macrolides, according to the FDA.

Two companies, Zoetis (Pfizer's animal-drug subsidiary) and Elanco, have the largest share of the animal antibiotic market. Both have said they will sign on to the FDA's program, Taylor said.

There was some initial praise for FDA's move.

"We commend FDA for taking the first steps since 1977 to broadly reduce antibiotic overuse in livestock," Laura Rogers, who directs the Pew Charitable Trusts' human health and industrial farming campaign, said in a statement. "There is more work to do, but this is a promising start -- especially after decades of inaction."

Not everyone, however, saw the changes as a step forward in controlling the use of antibiotics in food production.

"FDA's policy is an early holiday gift to industry. It is a hollow gesture that does little to tackle a widely recognized threat to human health," Avinash Kar, the health attorney for the Natural Resources Defense Council, said in a statement.

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