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    Oral Side Effects of Medications

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    Tooth Discoloration

    In the 1950s, doctors discovered that the use of tetracycline antibiotics during pregnancy led to brownish-color teeth in children. When a person takes tetracycline, some of the medicine settles into the calcium that the body uses to build teeth. When the teeth grow in, they are a yellowish-color, and they gradually turn brown when exposed to sunlight.

    Tetracycline, however, does not cause tooth discoloration if taken after all teeth are formed. It only causes a change in tooth color if you take it the medicine before the primary or secondary teeth come in.

    Today, tetracycline and related antibiotics are not recommended during pregnancy or in young children (under age 8) whose teeth are still forming.

    Other medicines are believed to affect materials in or on existing teeth, causing staining.

    The following medicines can cause brown, yellow-brown, or gray tooth discoloration:

    • amoxicillin-clavulanate (Augmentin), an antibiotic used to treat a number of bacterial infections
    • chlorhexidine, an antiseptic/disinfectant
    • doxycycline, an antibiotic related to tetracycline that is often used to treat acne
    • tetracycline, an antibiotic used to treat acne and some respiratory infections

    Too much fluoride (found in some chewable vitamins, toothpastes, and mouthwash) can lead to white streaks on the tooth enamel, or a whitish-brown discoloration. In severe cases, excess fluoride (called fluorosis) can lead to permanently stained brown teeth.

    The following drugs may cause greenish or a blue-green grayish color:

    • ciprofloxacin (Cipro), an antibiotic known as a quinolone
    • minocycline, an antibiotic related to tetracycline

    Iron salts taken by mouth can lead to black teeth.

    WebMD Medical Reference

    Reviewed by Alfred D. Wyatt Jr., DMD on August 09, 2014
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    Only 18.5% of Americans never floss. You are missing out on a simple way to make a big difference in the health of your mouth. Regardless of how well you brush, plaque still forms between your teeth and along your gums. Floss removes food trapped between the teeth and removes the film of bacteria that forms there before it turns to plaque, which can cause inflamed gums (gingivitis), cavities, and tooth loss. Try flossing just one tooth to get started.

    You are one of 31% of Americans who don't floss daily. You are missing out on a simple way to make a big difference in the health of your mouth. Regardless of how well you brush, plaque still forms between your teeth and along your gums. Toothbrush bristles alone cannot clean effectively between these tight spaces. Flossing removes up to 80% of the film that hardens to plaque, which can cause inflamed gums (gingivitis), cavities, and tooth loss. Aim for 3 more days!

    You are one of 31% of Americans who don't floss daily, but you're well on your way to making a positive impact on your teeth and gums. Regardless of how well you brush, plaque still forms between your teeth and along your gums. Toothbrush bristles alone cannot clean effectively between these tight spaces. Flossing removes up to 80% of the film that hardens to plaque, which can cause inflamed gums (gingivitis), cavities, and tooth loss. Aim for all 7 days!

    Only 50.5% of Americans floss daily, and good for you that you are one of them! Regardless of how well you brush, plaque still forms between your teeth and along your gums. Toothbrush bristles alone cannot clean effectively between these tight spaces. Flossing removes up to 80% of the film that hardens to plaque, which can cause inflamed gums (gingivitis), cavities, and tooth loss. Congratulations on your good oral health habit!

    SOURCES:

    American Dental Association, Healthy People 2010

    This tool is intended only for adults 18 and older.

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