Flossing And Brushing May Be Good For Your Brain
Feb. 14, 2000 (Atlanta) -- Following a dentist's advice may not seem like
the most likely way to protect the brain, but according to research presented
at a meeting in New Orleans, flossing and brushing may help prevent
Although past research has linked severe gum disease, or periodontitis, to
'hardening of the arteries,' stroke, and heart disease, Armin J. Grau, MD, and
researchers at the University of Heidelberg in Germany have undertaken what's
believed to be the first study of its kind looking at the link between
periodontitis and stroke.
Grau presented preliminary findings from his study at the American Stroke
Association's 25th International Stroke Conference. The research, which is
designed to examine 300 patients with stroke caused by a clot in the brain and
600 people for comparison who have not had a stroke, is ongoing, and is still
Periodontitis is an infection of the gums, the membranes at the base of the
teeth, and the supporting bone. As the natural barrier between the tooth and
gum erodes, bacteria from the inflammation and infection may be able to enter
the bloodstream. Those bacteria can increase plaque buildup in the arteries,
perhaps leading to clots.
Last July, preliminary data revealed that one-third more people who had had
a stroke were found to have severe periodontitis, compared with the control
group. On top of that, the odds "tended to increase," Grau writes, when
compared with other stroke risks such as previous stroke, high blood pressure,
diabetes, current and previous smoking, and even childhood socioeconomic
Maurizio Trevisan, MD, professor and chairman of the department of social
and preventive medicine at the University at Buffalo in New York, is the
co-author of another study that looked at the link between periodontal disease
and stroke. He and colleagues found that people with severe gum disease are
twice as likely to have the type of stroke brought on by clots than people with
good oral health.
Trevisan's study was made up of nearly 10,000 adults aged 25-75 and was
conducted from 1972-1974 with a follow-up completed in 1992.
"The majority of the studies seem to concur that [heart attack] patients
or people with heart disease have higher rates of periodontal disease than
people [who don't]," Trevisan tells WebMD. When he and his colleagues did
further analysis they saw that this "was not true only for heart disease,
but actually we find the association with stroke is even stronger."
Referring to the topic in general and to Grau's research, Trevisan says,
"It's a very interesting study, and I think it needs to be done." He
tells WebMD, "the sole idea of periodontitis, at least in our mind, is part
of this much larger interest, [a] resurgence and interest in the potential
etiological role of infection in [heart disease and stroke]."
- New studies show that people who have severe gum disease are more likely to
have a stroke.
- Researchers hypothesize that as the natural barrier between the tooth and
the gum erodes, bacteria from the infection enter the blood stream, damaging
- Past research has shown a similar association between gum disease and heart
disease, but the association with stroke seems to be even more pronounced.