Osteoarthritis Health Center
Arthritis Diets & Supplements: Do They Work?
By presidential proclamation, we're living in the National Bone and Joint Decade, 2002-2011, and that means we should be seeing a surge in research into causes and treatments of arthritis and other diseases.
Meanwhile, many people with osteoarthritis (OA) and rheumatoid arthritis (RA) seek relief by buying the latest book or nutritional supplement claiming to relieve or cure arthritis, or they take advice from a neighbor who swore that eating gin-soaked raisins eased her symptoms.
How do you navigate this gray area of unregulated therapies to know if what you're doing can help or harm? WebMD talked with two experts who provided insight into the claims made for arthritis diets and supplements. Hayes Wilson, MD, is a rheumatologist in Atlanta and medical adviser for the Arthritis Foundation. Christine Gerbstadt, RD, MD, practices in Pittsburgh and is a spokeswoman for the American Dietetic Association.
Here's a guide to help you sort fact from fiction:
Diets
- Eliminate nightshades. One of the most common diet claims is that eliminating nightshades, which include potatoes, tomatoes, eggplants, and most peppers, relieves arthritis. This diet probably isn't harmful, but there are no studies to support it.
- Alkaline diet. The alkaline diet presumes both OA and RA are caused by too much acid. Among the foods it excludes are sugar, coffee, red meat, most grains, nuts, and citrus fruits. It's meant to be followed for just one month. It may be that people feel better because they lose weight, reducing stress on joints, which eases pain. There are no studies to support it.
- Dong diet. This restrictive diet relies heavily on vegetables, except tomatoes, and eliminates many of the same foods as the alkaline diet. There's no evidence it affects arthritis.
- Vegetarian diet. Some people report improvement in symptoms, but evidence is mixed. One small study of people with RA showed improvement in four weeks, and follow-up studies of those who stayed on the diet showed continued improvement after one and two years.
- Switching fats. One of the known correlations between food and arthritis is that omega-6 fatty acids increase inflammation, and omega-3 fatty acids reduce it. Limit intake of meat and poultry, and increase your intake of cold-water fish, such as sardines, mackerel, trout, and salmon. For salad dressings and cooking, substitute olive, canola, and flaxseed oils for corn, safflower, and sunflower oils.
- Gin-soaked raisins. Lots of people claim it works, but experts say there's no evidence. Grapes and raisins do contain anti-inflammatory compounds, but not in amounts that would be therapeutic. The gin might dull pain, but drinking to excess sabotages health benefits of nutrients and vitamins, and introduces a whole new set of problems.
- Green tea. Drinking three to four cups of green tea a day could help people with RA. Studies funded by the Arthritis Foundation showed that giving the polyphenolic compounds in green tea to mice significantly decreased the incidence and severity of RA. Human studies have not yet confirmed the results.
Important Safety Information
Cymbalta® (duloxetine HCl) is approved for the treatment of depression and generalized anxiety disorder, and for the management of diabetic peripheral neuropathic pain and fibromyalgia.
What should I talk about with my healthcare provider?
Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, unusual changes in behavior, thoughts of suicide, anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, aggressiveness, impulsivity, restlessness, or extreme hyperactivity. Call your healthcare provider right away if you have thoughts of suicide or if any of these symptoms are severe or occur suddenly. Be especially observant within the first few months of antidepressant treatment or whenever there is a change in dose.
You should also know that:
- Suicide is a known risk of depression and some other psychiatric disorders.
- Antidepressants may increase suicidal thoughts or behaviors in some children, adolescents, and young adults especially within the first few months of treatment or when changing the dose. No increased risk has been shown for adults over age 24, and risk decreased for those over age 65.
- All patients starting therapy should be monitored appropriately and observed closely for new or worsening depression symptoms, suicidal thoughts or behavior, or unusual changes in behavior.
- Cymbalta® is not approved for use in patients under age 18.
Who should NOT take Cymbalta?
You should not take Cymbalta if:
- You have recently taken a type of antidepressant called a monoamine oxidase inhibitor (MAOI)
- You have uncontrolled narrow-angle glaucoma (an eye disease)
- You are taking Mellaril® (thioridazine)
What other important information should I discuss with my healthcare provider?
Before starting Cymbalta, tell your healthcare provider:
- about all of your medical conditions, including kidney problems, glaucoma, or diabetes
- about your alcohol use
- if you are taking nonprescription or prescription medicines, including those for migraine, to address a possible life threatening condition
- if you are taking NSAID pain relievers, aspirin, or blood thinners. Use with Cymbalta may increase bleeding risk
- if you are pregnant, plan to become pregnant during therapy, or are breastfeeding an infant
While taking Cymbalta, tell your healthcare provider:
- if you have itching, right upper belly pain, dark urine, yellow skin/eyes, or unexplained flu-like symptoms, which may be signs of liver problems. Severe liver problems, sometimes fatal, have been reported
- if you have high fever, confusion, and stiff muscles to address a possible life-threatening condition
- before stopping Cymbalta or changing your dose
- if you experience dizziness or fainting upon standing, especially when first starting Cymbalta or when increasing the dose. Your healthcare provider may periodically check your blood pressure while you are taking Cymbalta
If you have any questions, talk to your healthcare provider before taking Cymbalta.
What are the possible side effects of Cymbalta?
The most common side effect of Cymbalta was nausea. For most people who had it, the nausea was mild to moderate. Other common side effects included dry mouth, sleepiness, constipation, decreased appetite, and, increased sweating. This is not a complete list of side effects.
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