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A Different Type of Osteoarthritis Treatment

Did you know that osteoarthritis knee pain is caused by more than just cartilage loss?

In knees with osteoarthritis, the joint fluid also loses its ability to absorb shock, which can result in osteoarthritis knee pain. A viscosupplement injection is a treatment that supplements your natural joint fluid to give your knee the lubrication and cushioning it needs to provide osteoarthritis knee pain relief.


What is Synvisc-One?

Synvisc-One is a one-injection treatment that supplements the fluid in your knee to help lubricate and cushion the joint. Synvisc-One is the #1 prescribed viscosupplement; it provides up to six months of osteoarthritis knee pain relief with just one injection.*

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How can Synvisc-One help relieve my osteoarthritis knee pain?

How Synvisc-One Works

Knee with Osteoarthritis Before Synvisc-One InjectionIn knees with osteoarthritis, the cartilage gradually deteriorates, joint fluid loses its shock-absorbing qualities, and bones may begin to rub against each other—all of which may cause bone spurs and the knee pain you're feeling.

Knee with Osteoarthritis After Synvisc-One InjectionSynvisc-One lubricates and cushions your knee. It is a single-dose injection that supplements your knee joint fluid to relieve the pain for up to six months.*

How do I know if Synvisc-One is right for me?

Synvisc-One is for people with knee osteoarthritis who have not received enough pain relief from diet, exercise, and over-the-counter pain medication. If you've tried these options and are still feeling knee pain, ask your doctor if Synvisc-One could help.


What is Synvisc-One made from?

The injection contains a gel-like mixture made from a substance called hyaluronan (pronounced hy-aI-u-ROE-nan) that comes from chicken combs. Hyaluronan is a natural substance found in the body and is present in very high amounts in joints. The body's own hyaluronan acts like a lubricant and a shock absorber in the joint and is needed for the joint to work properly.


Will the injection hurt?

The doctor will likely apply a numbing agent before a Synvisc-One injection. You may feel some pressure.


What are the side effects?

The most common side effects are pain, swelling, heat, redness and/or fluid build-up around the knee. In a medical study less than 6% of patients experienced these side effects, which were generally mild and did not last long.


Is it covered by insurance?

Synvisc-One is covered by Medicare and most insurance plans.


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What does my doctor need to know about my osteoarthritis knee pain?

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Get up to six months of osteoarthritis knee pain relief with Synvisc-One.*

You don't need to be in constant pain to be ready for a different treatment.

Receive a FREE Osteoarthritis Knee Pain Relief Info Kit to learn more about Synvisc-One today.


Tools to Help Relieve Your Osteoarthritis Knee Pain:


* As shown in a medical study comparing Synvisc-One to an injection of salt water.


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Indication

Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Important Safety Information for Synvisc-One

Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, or circulatory problems in the legs.

Synvisc-One is only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds – such as feathers, eggs or poultry – or if your leg is swollen or infected.

Synvisc-One has not been tested in children (≤21 years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.

Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. Tell your doctor if you experience any side effects after treatment with Synvisc-One.

View the complete prescribing information for Synvisc-One. (PDF)

©2014 Genzyme Corporation, a Sanofi Company.
All rights reserved. Synvisc-One, SYNVISC and GENZYME are registered trademarks of Genzyme Corporation.
US.SYN.14.01.047

WebMD does not endorse any specific product, service, or treatment.

Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Important Safety Information for Synvisc-One
Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products.
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