Over-the-Counter Pain Relievers: Medications continued...
In addition, NSAIDs block the production of substances that line and protect the stomach from acids; when taken long term, some NSAID users can experience side effects related to stomach irritation and bleeding. Your doctor may recommend you take a medication such as omeprazole ( Prilosec), esomeprazole ( Nexium), pantoprazole ( Protonix), ranitidine ( Zantac), or famotidine ( Pepcid) to protect your stomach. You’re at particular risk for side effects if you’re over age 75, take high doses of NSAIDs or take them over an extended period of time, or are on medications to prevent blood clots.
Other OTC Pain Relievers
Among the most popular supplements used by people with osteoarthritis are glucosamine and chondroitin. In those with moderate to severe knee pain from osteoarthritis, the combination of glucosamine and chondroitin sulfate may be effective in providing pain relief, although medical studies have not shown clear proof that they are helpful in everyone.
There do not seem to be any major side effects from glucosamine and chondroitin supplements, but because they are supplements, they are not regulated by the FDA the same way as drugs. That means that there is no way to be sure of the content and quality of supplements sold in stores.
Skin creams made from capsaicin, an extract from chili peppers, may help relieve mild arthritis pain when applied to the skin, although these creams have not shown consistent benefit in medical studies They cause a mild stinging or burning sensation in about half of people using them, which usually fades over time.
Applying ice or warm compresses to the affected joint a few times per week may also improve pain, swelling, and range of motion. Ice therapy may also be helpful immediately after activities such as exercise.
Prescription Drugs: NSAIDs
In addition to over-the-counter NSAID medications, you can also ask your doctor for a prescription for NSAIDs to treat arthritis pain and inflammation. Some of these are merely stronger versions of the NSAIDs you can buy over the counter, like prescription-strength ibuprofen. Prescription NSAIDs may also be available in topical and injectable forms. Besides ibuprofen and naproxen, other examples of prescription NSAIDs include diclofenac ( Arthrotec, Cataflam, Voltaren), etodolac ( Lodine), meloxicam ( Mobic), and piroxicam ( Feldene).