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Hope for Joint Pain

Reviewed By: Louise Chang,

SOURCES: 2007 Medical Reference from Medstar Television. John Szivek, Ph.D., Orthopaedic Research, Director, University of Arizona, Tucson, AZ.

© 1999-2011 Medstar Television

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Narrator:

Bill Brown loves to be outdoors. He's a volunteer firefighter and rescue worker, but even yard work has started taking its toll.

Bill Brown:

I finally went to a doctor to see why I was in such pain and really having a hard time even walking in the daily routine.

Narrator:

Bill was diagnosed with osteoarthritis.

Bill Brown:

I don't feel like I really have the strength to resume some of the rigorous activities that I was doing before.

Narrator:

A quick fix for Bill's arthritis might be brewing in this research lab. Doctor John Szivek (SEE-vick) and his team are working on an alternative to joint replacement.

John Szivek, Ph.D.:

There seem to be a lot of stem cells in fat and if you can extract those cells from the fat tissue, it's fairly straight forward to convert them to cartilage cells using a number of different strategies.

Narrator:

Once removed, a patient's fat cells would be manipulated in the lab, then surgically implanted back into the patient's ailing joint.

John Szivek, Ph.D.:

We would create something called a scaffold, and we will collect the cells, grow the tissue on that scaffold and then place it into the patient.

Narrator:

The scaffold is made of porous material that will be absorbed by the body and replaced with the patient's own tissue.

John Szivek, Ph.D.:

The scaffold allows time for the cells to form a high end cartilage like material which is the type of cartilage that you have in your joint.

Bill Brown:

I would certainly be for doing that, then having a knee replacement.

Narrator:

Doctor Szivek expects it to be another few years before this advance could make it to market… but the future looks promising. For WebMD, I'm Damon Meharg.

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