Paget's disease is a chronic disease that affects how
the body breaks down and rebuilds bone tissue. Paget's disease can be active or
inactive, depending on whether the bone formation process goes too quickly or
Reality: If diagnosed, osteoporosis can be treated with a variety of new osteoporosis medications that help to prevent bone loss and rebuild bone. These osteoporosis treatments can substantially reduce your risk of developing dangerous and potentially deadly bone fractures.
Antiresorptive medications affect the body's bone remodeling cycle by slowing or stopping the part of the process that involves breakdown of bone. This can both prevent the onset of osteoporosis and help treat the disease...
In inactive Paget's disease,
bone tissue is being broken down and rebuilt at a
normal speed. This most often occurs when you are using medicine to slow the
bone growth. The inactive state may continue even after you stop taking
medicine. This is called
Active Paget's disease
Active Paget's disease has three stages. They are:
Hot (lytic) stage. This stage occurs early in the
disease process, when bone tissue is being quickly broken down. Bones are often
more painful during this stage.
Mixed stage. This stage occurs
later in the disease process, when bone tissue is being quickly broken down and
Cold (rebuilding) stage. This stage occurs later
in the disease, when bone tissue is being quickly rebuilt.
Bone pain may occur in any of the stages.
Primary Medical Reviewer
Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer
Jennifer Hone, MD, MD - Endocrinology, Diabetes and Metabolism
September 1, 2011
WebMD Medical Reference from Healthwise
September 01, 2011
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