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Osteoporosis Health Center

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The Truth About Vitamin D: Drug Interactions

WebMD feature series on vitamin D.
WebMD Feature

Does vitamin D interact with other medications?

Yes. Steroid medications such as prednisone can interfere with vitamin D metabolism. If you take steroid drugs regularly, discuss vitamin D with your doctor.

The weight loss drug orlistat -- brand names include Xenical and Alli -- may cut absorption of vitamin D. So does the cholesterol-lowering drug cholestyramine (sold as Questran, LoCholest, and Prevalite). People taking these drugs should discuss vitamin intake with their doctors.

The seizure drugs Phenobarbital and Dilantin (phenytoin), affect vitamin D metabolism and affect calcium absorption. So do anti-tuberculosis drugs.

On the other hand, cholesterol-lowering statin drugs and thiazide diuretics increase vitamin D levels.

First: Introduction to vitamin D next button

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Reviewed on December 17, 2009

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