Osteoporosis Health Center
Osteopenia: Early Signs of Bone Loss
About 18 million Americans have osteopenia. Osteopenia refers to early signs of bone loss that can turn into osteoporosis. With osteopenia, bone mineral density is lower than normal. However, it is not yet low enough to be considered osteoporosis.
Not everyone who has osteopenia develops osteoporosis with its painful, debilitating fractures. But osteopenia can turn into osteoporosis if it is not diagnosed early and promptly treated. Osteoporosis can result in easily fractured bones and other very serious bone problems. It can also cause disfigurement and lead to loss of mobility and independence.
How can my doctor determine if I have osteopenia?
Bone health is measured in two ways. The first is bone density. Bone density defines the thickness of your bone. The second is bone mass. Bone mass means how much bone you have.
What does my doctor measure to determine my bone density and risk for osteopenia?
To find bone density, your doctor measures the levels of minerals in your bones. These minerals include:
- calcium
- phosphate
- other minerals
The denser the content of your bone mineral is, the stronger your bones are.
With aging, your body absorbs back calcium and other minerals from your bones. This reabsorption can make your bones weaker and lead to osteopenia and osteoporosis. The bones become more vulnerable to fractures and other damage.
At what age does bone mass start to decline?
Bone mass, or the amount of bone you have, usually peaks around age 30. Then bone mass begins to decline. Your body starts to reabsorb bone faster than new bone can be made.
How do I know if I'm at risk for osteopenia or osteoporosis?
Most people with osteopenia don't know it. In fact, the first sign may be a broken bone. A broken bone may mean that the condition has already become osteoporosis.
What are some risk factors for osteopenia and osteoporosis?
Risk factors for developing osteopenia are the same as those for developing osteoporosis. They include:
- being female
- being thin and/or having a small frame
- getting too little calcium in the diet
- smoking
- leading an inactive lifestyle
- a history of anorexia nervosa
- a family history of osteoporosis
- heavy alcohol consumption
- early menopause
For in-depth information, see WebMD's Self-Test: Check Your Risk.
How can my doctor test for osteopenia and osteoporosis?
The most accurate way to diagnose osteopenia and osteoporosis is through bone mineral density testing. This is usually done with a dual-energy X-ray absorptiometry (DEXA) scan.
DEXA scan results are reported as T-scores:
- Normal bone: T-score above -1
- Osteopenia: T-score between -1 and -2.5
- Osteoporosis: T-score below -2.5
Other tests can be done to help diagnose osteoporosis and osteopenia. Quantitative ultrasound is one such test. It measures the speed of sound in the bone to assess bone density and strength. DEXA scans are usually still needed to confirm results from ultrasound and other tests.
For in-depth information, see WebMD's Diagnosing Osteoporosis.
WebMD Medical Reference
VIVELLE-DOT (estradiol transdermal system) IS AVAILABLE BY PRESCRPTION ONLY.
INDICATION
Vivelle-Dot is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; help reduce your chances of getting osteoporosis (thin weak bones); and treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally. Vivelle-Dot 0.025 mg/day is only used to prevent osteoporosis from menopause. If you use Vivelle-Dot only to treat your dryness, itching, and burning in and around your vagina or if you use Vivelle-Dot only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.
IMPORTANT SAFETY INFORMATION
Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia (decline in memory and thinking skills).
Vivelle-Dot should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.
The most common side effects that may occur with Vivelle-Dot are headache, breast tenderness, and back pain.
You and your healthcare professional should talk regularly about whether you still need treatment with Vivelle-Dot.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information for Vivelle-Dot.

