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Ovarian Cancer Guide

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Ovarian Cancer Health Center

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Exams and Tests

Some exams and tests that are done to look for or diagnose ovarian cancer include:

A biopsy, which is the only way to know for sure if a woman has ovarian cancer. This usually is done with a laparotomy, through a cut (incision) in the belly.
A physical exam, including a pelvic exam and Pap test. An ovarian lump may be felt during a pelvic exam. A rectovaginal exam may also be done to feel the pelvic organs.
A cancer antigen 125 (CA-125) level, to measure a protein found on the surface of many ovarian cancer cells.
A pelvic and transvaginal ultrasound, to look for an ovarian lump.
A pelvic or abdominal CT scan or MRI, to check for the spread of cancer.

Early detection

The United States Preventive Services Task Force (USPSTF) doesn't recommend routine screening for ovarian cancer.⁶ There is no proof that having regular tests helps women live longer by finding ovarian cancer early.

Recommended Related to Ovarian Cancer

General Information About Ovarian Epithelial Cancer

Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) Incidence and Mortality Estimated new cases and deaths from ovarian cancer in the United States in 2011:[1] New cases: 21,990. Deaths: 15,460. Several malignancies...

Read the General Information About Ovarian Epithelial Cancer article > >

Still, some experts recommend that women who have inherited a BRCA gene change and have not had their ovaries removed have a transvaginal ultrasound and a CA-125 blood test at least once a year, starting at age 35. Women who have inherited a BRCA1 gene change (not a BRCA2 gene change) may want to start having these tests as early as age 25.⁷

WebMD Medical Reference from Healthwise

Last Updated: July 06, 2011

This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.