Ovarian Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Description of the Evidence
PathogenesisThe pathogenesis of ovarian carcinoma remains unclear. Several theories have been proposed to explain the epidemiology of ovarian cancer including the theory of incessant ovulation,[1,2] gonadotropin stimulation, excess androgenic stimulation, and inflammation. Associated risk factors for ovarian cancer support some or all of these hypotheses. Oral contraceptive use is consistently associated with a decreased risk of ovarian cancer and may operate through preventing the trauma from repeated ovulation by lowering exposure to gonadotropins. No one theory, however, explains all the associated risk factors.Protective Factors Factors associated with a decreased risk of ovarian cancer include: (1) using oral contraceptives, (2) having and breastfeeding children, (3) having a bilateral tubal ligation or hysterectomy, and (4) having a prophylactic oophorectomy.Oral contraceptives Multiple studies have consistently demonstrated a decrease in
Ovarian Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Changes to This Summary (09 / 11 / 2014)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.
Ovarian Cancer Screening (PDQ®): Screening - Patient Information [NCI] - General Information About Ovarian Low Malignant Potential Tumors
Ovarian low malignant potential tumor is a disease in which abnormal cells form in the tissue covering the ovary. Ovarian low malignant potential tumors have abnormalcells that may become cancer,but usually do not. This disease usually remains in the ovary. When disease is found in one ovary,the other ovary should also be checked carefully for signs of disease. The ovaries are a pair of ...
Ovarian Low Malignant Potential Tumors Treatment (PDQ®): Treatment - Patient Information [NCI] - About This PDQ Summary
About PDQPhysician Data Query (PDQ) is the National Cancer Institute's (NCI's) comprehensive cancer information database. The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries come in two versions. The health professional versions have detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions have cancer information that is accurate and up to date and most versions are also available in Spanish.PDQ is a service of the NCI. The NCI is part of the National Institutes of Health (NIH). NIH is the federal government's center of biomedical research. The PDQ summaries are based on an independent review of the medical literature. They are not policy statements of the NCI or the NIH.Purpose of This SummaryThis PDQ cancer information summary has current
Ovarian Germ Cell Tumors Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage I Ovarian Germ Cell Tumors
DysgerminomasStandard treatment options:Unilateral salpingo-oophorectomy with or without lymphangiography or computed tomography (CT).Unilateral salpingo-oophorectomy followed by observation.Unilateral salpingo-oophorectomy with adjuvant radiation therapy or chemotherapy.For patients with stage I dysgerminoma, unilateral salpingo-oophorectomy conserving the uterus and opposite ovary is accepted treatment of the younger patient who wants to preserve fertility or a pregnancy. Postoperative lymphangiography or CT is indicated before treatment decisions are made for patients who have not had careful surgical and pathological examination of pelvic and para-aortic lymph nodes during surgery. (Refer to the PDQ summary on Sexuality and Reproductive Issues for more information on fertility.)Patients who have been completely staged and have stage IA tumors may be observed carefully after surgery without adjuvant treatment. About 15% to 25% of these patients will relapse, but they can be treated
Ovarian Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - General Information About Ovarian Germ Cell Tumors
Germ cell tumors of the ovary are uncommon,but aggressive,tumors,which are seen most often in young women or adolescent girls. These tumors are frequently unilateral and are generally curable if found and treated early. The use of combination chemotherapy after initial surgery has dramatically improved the prognosis for many women with these tumors.[ 1,2,3 ] Dysgerminomas One series ...
Ovarian Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - Stage II Ovarian Germ Cell Tumors
DysgerminomasStandard treatment options: Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant radiation therapy or chemotherapy.Unilateral salpingo-oophorectomy with adjuvant chemotherapy.For patients with stage II dysgerminoma, total abdominal hysterectomy and bilateral salpingo-oophorectomy are usually performed. For the younger patient who wants to preserve fertility, a unilateral salpingo-oophorectomy may be considered standard therapy, depending on the age of the patient, and adjuvant chemotherapy should be given. (Refer to the PDQ summary on Sexuality and Reproductive Issues for more information on fertility.)These patients should receive adjuvant treatment. Options include radiation therapy or chemotherapy. A disadvantage of the former is loss of fertility resulting from ovarian failure. Experience with adjuvant chemotherapy is limited, but considering the effectiveness of chemotherapy in tumors other than dysgerminoma and its effectiveness in
Ovarian Cancer Screening (PDQ®): Screening - Patient Information [NCI] - nci_ncicdr0000062941-nci-header
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Ovarian Low Malignant Potential Tumors Treatment
Important It is possible that the main title of the report Bartter's Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...
Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI
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