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    Ovarian Cancer Health Center

    Medical Reference Related to Ovarian Cancer

    1. Bartter's Syndrome

      Important It is possible that the main title of the report Bartter's Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...

    2. Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview

      Standard treatment options for patients with ovarian germ cell tumors include:Surgery.Chemotherapy.Radiation therapy.Patients may be treated with unilateral salpingo-oophorectomy or total abdominal hysterectomy and bilateral salpingo-oophorectomy.All patients except those with stage I, grade I immature teratoma and stage IA dysgerminoma require postoperative chemotherapy. With platinum-based combination chemotherapy, the prognosis for patients with endodermal sinus tumors, immature teratomas, embryonal carcinomas, choriocarcinomas, and mixed tumors containing one or more of these elements has improved dramatically.[1] As new and more effective drugs are developed, many of these patients will be candidates for newer clinical trials.Treatment options under clinical evaluation for patients with ovarian germ cell tumors include:High-dose chemotherapy with bone marrow transplant.New treatment options.References: Gershenson DM, Morris M, Cangir A, et al.: Treatment of malignant germ cell

    3. Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview

      There are different types of treatment for patients with ovarian germ cell tumors. Different types of treatment are available for patients with ovarian germ cell tumor. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment.Four types of standard treatment are used: SurgerySurgery is the most common treatment of ovarian germ cell tumor. A doctor may take out the cancer using one of the following types of surgery. Unilateral salpingo-oophorectomy: A surgical procedure to remove one ovary and one fallopian

    4. Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - About This PDQ Summary

      Purpose of This SummaryThis PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of ovarian epithelial cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.Reviewers and UpdatesThis summary is reviewed regularly and updated as necessary by the PDQ Adult Treatment Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH). Board members review recently published articles each month to determine whether an article should:be discussed at a meeting,be cited with text, orreplace or update an existing article that is already cited.Changes to the summaries are made through a consensus

    5. Ovarian Germ Cell Tumors Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Ovarian Germ Cell Tumors

      Germ cell tumors of the ovary are uncommon,but aggressive,tumors,which are seen most often in young women or adolescent girls. These tumors are frequently unilateral and are generally curable if found and treated early. The use of combination chemotherapy after initial surgery has dramatically improved the prognosis for many women with these tumors.[ 1,2,3 ] Dysgerminomas One series ...

    6. Ovarian Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Changes to This Summary (06 / 12 / 2014)

      The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.

    7. Oophorectomy - Overview

      Note: Separate PDQ summaries on Ovarian Cancer Prevention; Ovarian Epithelial Cancer Treatment; Ovarian Germ Cell Tumor Treatment; and Ovarian Low Malignant Potential Tumor Treatment are also available. Evidence of Benefit or Lack of Benefit Associated with ScreeningSingle-threshold cancer antigen 125 (CA-125) levels and transvaginal ultrasound (TVU)There is solid evidence to indicate that routine screening for ovarian cancer with the serum marker CA-125 and TVU does not result in a decrease in mortality from ovarian cancer.Magnitude of Effect: No reduction in mortalityStudy Design: Evidence obtained from one randomized controlled trial.Internal Validity: Good.Consistency: One trial has evaluated the impact on mortality from ovarian cancer.External Validity: Good.Statement of HarmsBased on solid evidence, routine screening for ovarian cancer results in false-positive test results among 9.6% of those screened; of those with false-positive results who had surgery, the complication rate

    8. Ovarian Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Changes to This Summary (09 / 11 / 2014)

      The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.

    9. Oophorectomy - Changes to This Summary (07 / 09 / 2012)

      The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Stage Information for Ovarian Low Malignant Potential Tumors Updated staging information for 2010 (cited FIGO Committee on Gynecologic Oncology and Edge et al. as references 1 and 2, respectively).This summary is written and maintained by the PDQ Adult Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

    10. Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Description of the Evidence

      BackgroundIncidence and mortalityOvarian cancer is the fifth leading cause of cancer death among women in the United States and has the highest mortality rate of all gynecologic cancers.[1] It is estimated that 22,240 new cases of ovarian cancer will be diagnosed in the United States in 2013, and 14,030 women will die of this disease.[1] The median age at diagnosis is 63 years.[2] The prognosis for survival from ovarian cancer largely depends on the extent of disease at diagnosis, which is usually advanced, with only about 15% of women presenting with localized disease at diagnosis.[1,2]From 2005 to 2009, incidence rates decreased by 0.9% per year, and mortality rates decreased by 2.0% per year.[1]Ovarian cancer is rare; the lifetime risk of being diagnosed with ovarian cancer is 1.38%.[2]Types of Ovarian CancerThe term ovarian cancer encompasses a heterogeneous group of malignant tumors of ovarian origin that may arise from germ cells, stromal tissue, or

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