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Ovarian Cancer Health Center

Medical Reference Related to Ovarian Cancer

  1. Ovarian Germ Cell Tumors Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage III Ovarian Germ Cell Tumors

    DysgerminomasStandard treatment options:Total abdominal hysterectomy and bilateral salpingo-oophorectomy.Unilateral salpingo-oophorectomy with adjuvant chemotherapy.For patients with stage III dysgerminoma, total abdominal hysterectomy and bilateral salpingo-oophorectomy are recommended with removal of as much gross tumor as can be done safely without resection of portions of the urinary tract or large segments of the small or large bowel. Patients who want to preserve fertility may be treated with unilateral salpingo-oophorectomy if chemotherapy is to be employed.[1,2,3,4,5] (Refer to the PDQ summary on Sexuality and Reproductive Issues for more information on fertility.)Combination chemotherapy with bleomycin, etoposide, and cisplatin (BEP) can cure the majority of such patients. In a report of results from two Gynecologic Oncology Group (GOG) trials, 19 of 20 patients with incompletely resected tumors who were treated with BEP or cisplatin, vinblastine, and bleomycin (PVB) were

  2. Ovarian Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - Ovarian Cancer Prevention

    Avoiding risk factors and increasing protective factors may help prevent cancer.Avoiding cancer risk factors may help prevent certain cancers. Risk factors include smoking, being overweight, and not getting enough exercise. Increasing protective factors such as quitting smoking, eating a healthy diet, and exercising may also help prevent some cancers. Talk to your doctor or other health care professional about how you might lower your risk of cancer.The following risk factors may increase the risk of ovarian cancer:Family history of ovarian cancerA woman whose mother or sister had ovarian cancer has an increased risk of ovarian cancer. A woman with two or more relatives with ovarian cancer also has an increased risk of ovarian cancer. Inherited riskThe risk of ovarian cancer is increased in women who have inherited certain changes in the following genes:BRCA1 or BRCA2 genes.Genes that are linked to hereditary nonpolyposis colorectal cancer (HNPCC; Lynch syndrome).Hormone replacement

  3. Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Ovarian Epithelial Cancer

    The following is a list of ovarian epithelial cancer histologic classifications. Serous cystomas: Serous benign cystadenomas.Serous cystadenomas with proliferating activity of the epithelial cells and nuclear abnormalities but with no infiltrative destructive growth (low potential or borderline malignancy).Serous cystadenocarcinomas.Mucinous cystomas: Mucinous benign cystadenomas.Mucinous cystadenomas with proliferating activity of the epithelial cells and nuclear abnormalities but with no infiltrative destructive growth (low potential or borderline malignancy).Mucinous cystadenocarcinomas.Endometrioid tumors (similar to adenocarcinomas in the endometrium): Endometrioid benign cysts.Endometrioid tumors with proliferating activity of the epithelial cells and nuclear abnormalities but with no infiltrative destructive growth (low malignant potential or borderline malignancy).Endometrioid adenocarcinomas.Clear cell (mesonephroid) tumors: Benign clear cell tumors.Clear cell tumors with

  4. Ovarian Germ Cell Tumors Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options By Stage

    A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.Stage I Ovarian Germ Cell TumorsTreatment depends on whether the tumor is a dysgerminoma or another type of ovarian germ cell tumor. Treatment of dysgerminoma may include the following: Unilateral salpingo-oophorectomy with or without lymphangiography or CT scan.Unilateral salpingo-oophorectomy followed by observation.Unilateral salpingo-oophorectomy followed by radiation therapy.Unilateral salpingo-oophorectomy followed by chemotherapy.Treatment of other ovarian germ cell tumors may be either: unilateral salpingo-oophorectomy followed by careful observation; orunilateral salpingo-oophorectomy, sometimes followed by combination chemotherapy.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting

  5. Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Ovarian Epithelial Cancer

    Ovarian epithelial cancer is a disease in which malignant (cancer) cells form in the tissue covering the ovary. The ovaries are a pair of organs in the female reproductive system. They are located in the pelvis,one on each side of the uterus (the hollow,pear-shaped organ where a fetus grows). Each ovary is about the size and shape of an almond. The ovaries produce eggs and female hormones ...

  6. Ovarian Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

  7. Ovarian Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  8. Ovarian Low Malignant Potential Tumors Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Ovarian Low Malignant Potential Tumors

    A link to a list of current clinical trials is included for each treatment section. For some stages, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.Early Stage Ovarian Low Malignant Potential Tumors (Stage I and II)Surgery is the standard treatment for early stage ovarian low malignant potential tumor. The type of surgery usually depends on whether a woman plans to have children.For women who plan to have children, surgery is either:unilateral salpingo-oophorectomy; orpartial oophorectomy.To prevent recurrence of disease, most doctors recommend surgery to remove the remaining ovarian tissue when a woman no longer plans to have children.For women who do not plan to have children, treatment may be hysterectomy and bilateral salpingo-oophorectomy.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I borderline ovarian surface epithelial-stromal

  9. Ovarian Epithelial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  10. Ovarian Germ Cell Tumors Treatment (PDQ®): Treatment - Patient Information [NCI] - About This PDQ Summary

    About PDQPhysician Data Query (PDQ) is the National Cancer Institute's (NCI's) comprehensive cancer information database. The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries come in two versions. The health professional versions have detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions have cancer information that is accurate and up to date and most versions are also available in Spanish.PDQ is a service of the NCI. The NCI is part of the National Institutes of Health (NIH). NIH is the federal government's center of biomedical research. The PDQ summaries are based on an independent review of the medical literature. They are not policy statements of the NCI or the NIH.Purpose of This SummaryThis PDQ cancer information summary has current

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