Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Ovarian Cancer Health Center

Font Size

Progress in Blood Test to Detect Ovarian Cancer

Researchers Study Test That May Flag Early Stages of Ovarian Cancer
WebMD Health News

May 9, 2005 -- Researchers report progress in developing a blood test for ovarian cancer,ovarian cancer, the leading cause of gynecological cancer death.

The test screens blood for four proteins -- leptin, prolactin, osteopontin, and insulin-like growth factor II -- and may detect early stages of ovarian cancer, say Gil Mor, MD, and colleagues.

"Early diagnosis can help prolong or save lives, but clinicians currently have no sensitive screening method because the disease shows few symptoms," says Mor in a news release. Mor is an associate professor of obstetrics, gynecology, and reproductive sciences at Yale University's medical school.

About Ovarian Cancer

Ovarian cancer often has few early symptomsfew early symptoms and is often diagnosed late, when chances of survival are poor, says Mor's study, which appears in the early edition of Proceedings of the National Academy of the Sciences of the United States of America.

This year, about 22,000 U.S. women will be diagnosed with ovarian cancer and 16,210 will die from it, says the American Cancer Society (ACS). The main reason for the poor outcome is the advanced stage of the cancer at the time of diagnosis in most cases. Symptoms appear only in the late stages of the disease.

The overall five-year survival is only 20%-30%, according to the American College of Obstetricians and Gynecologists (ACOG). However, women diagnosed at earlier stages have a better probability of a cure.

Ovarian cancer rates have gone down since 1991, says the ACS, noting that a woman's risk of getting ovarian cancer in her lifetime is about one in 58. Her risk of dying from ovarian cancer is one in 98, says the ACS.

About 80% of ovarian cancer patients are diagnosed with advanced stages of the disease, say Mor and colleagues. "In patients with advanced disease, 80% to 90% will initially respond to chemotherapy, but [less than] 10-15% will remain in permanent remission," they write.

For women diagnosed at early stages (stages I or II), five-year survival is 60% to 90%, says the study.

"Currently, it appears that the best way to detect early ovarian cancer is for both the patient and her clinician to have a high index of suspicion of the diagnosis in a symptomatic woman," says ACOG. Unfortunately there is no screening test for ovarian cancer that has proved effective in screening low-risk asymptomatic women, they add.

Today on WebMD

Ovarian cancer illustration
What are the symptoms?
doctory with x-ray
Get to know the Symptoms.
cancer cell
HPV is the top cause. Find out more.
Lung cancer xray
See it in pictures, plus read the facts.
Integrative Medicine Cancer Quiz
Lifestyle Tips for Depression Slideshow
Screening Tests for Women
Graphic of ovaries within reproductive system
Ovarian Cancer Marker
Pets Improve Your Health
Vitamin D
Healthy meal with salmon