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Pain Management Health Center

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Pain Management: Chronic Pain and Depression

Depression is one of the most common problems experienced by people with chronic pain. It is no wonder -- chronic pain can significantly affect a person's quality of life.

If symptoms of depression are related to pain or side effects of a medicine, doctors can make adjustments in medications to alleviate these symptoms. If the depression is a separate problem, it can be treated on its own.

Recommended Related to Pain Management

Dupuytren's Contracture: Causes, Symptoms, and Treatment

Dupuytren's contracture is an abnormal thickening and tightening of the normally elastic tissue beneath the skin of the palm and fingers. This tissue is called fascia. The fascia contains strands of fibers, like cords, that run from the palm upward into the fingers. In Dupuytren's contracture, these cords tighten, or contract, causing the fingers to curl forward. In severe cases, it can lead to crippling hand deformities.

Read the Dupuytren's Contracture: Causes, Symptoms, and Treatment article > >

Treating Pain and Depression

Most people with depression can be treated successfully with medicine, psychotherapy, or a combination of both.

Antidepressant Therapy

In addition to being a primary treatment for depression, some antidepressants are effective in the treatment of many chronic pain syndromes, such as nerve-related pain disorders.

Antidepressant drugs work by altering the functioning of brain regions that are controlled by chemicals in the brain called neurotransmitters, which are responsible for transferring messages between brain cells. Some antidepressants include:


Psychotherapy, sometimes also called talk therapy, refers to a variety of techniques used to treat depression. Psychotherapy involves talking to a licensed professional who helps the depressed person:

  • Focus on the behaviors, emotions, and ideas that contribute to depression
  • Understand and identify the life problems or events, such as a major illness, a death in the family, a loss of a job, or a divorce, that contribute to depression, and help them understand which aspects of those problems they may be able to solve or improve
  • Regain a sense of control and pleasure in life

Early Treatment Is Best

Early diagnosis and treatment for depression can help reduce distress, as well as the risk of complications and suicide. People who get treatment for depression that occurs at the same time as chronic pain often experience an improvement in their overall medical condition, a better quality of life, and are more easily able to stick to their treatment plans.

WebMD Medical Reference

Reviewed by Joseph Goldberg, MD on April 19, 2015

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