Skip to content

    Pain Management Health Center

    Font Size
    A
    A
    A

    Track DMARD Effects

    DMARDs are often standard treatment for rheumatoid arthritis. Even if you've been taking them a while, you still need to track how well they work and watch for side effects. Set aside time to review what to expect from DMARD treatment and the precautions you need to take.

    Treat Nausea

    Do methotrexate pills upset your stomach? It's a common side effect. Symptoms may be worst the first day or so after your weekly dose.

    Ask your doctor which treatments can help. A folic acid supplement after your methotrexate may ease nausea. Another option is to see if you can take methotrexate by injection instead. When injected, the drug no longer goes through your stomach. Some people find that helps with nausea.

    Plaquenil and Eyes

    Anyone taking Plaquenil should see an eye doctor on a regular basis for an eye checkup. Although it's rare, Plaquenil can sometimes cause degeneration of the retina, which could lead to vision loss. A regular eye exam -- even if you don't wear glasses -- can help catch any potential problems early and avoid serious consequences. Ask your eye doctor how often you need an exam. It's usually annually, but frequency varies based on your risk factors.

    Folic Acid Help

    Folic acid may also help with many of the other common side effects from methotrexate, such as fatigue, headaches, hair loss, and oral ulcers. Ask your doctor if folic acid might help you -- don't just start taking it on your own. Many people using this DMARD take daily folic acid supplements. Some people may take a prescription form of folic acid called leucovorin that you typically take once a week. Talk to your doctor about what's right for you.

    DMARDs and Pregnancy

    Some DMARDs can cause serious birth defects. Anyone using these drugs needs to use birth control to prevent an unexpected pregnancy.

    If you're thinking about getting pregnant, talk to your doctor before you start trying. You may need to stop taking some meds for several months before trying to conceive. Your doctor may switch you to other meds to help control your RA symptoms.

    DMARDs and Illness

    DMARDs increase the risk of infection. Call your doctor if you notice any of these signs of infection:

    * Fever

    * Chills

    * Sore throat

    * Cough

    If you do have an infection, you may need to get treated right away. Your doctor may also recommend that you stop taking the DMARD until you're better. However, never stop taking your DMARD -- or other prescribed medication -- without your doctor's approval. It could affect your RA and other health issues.

    DMARD Testing

    Make sure you go to checkups so your doctor can keep tabs on your overall health. How often you need one depends on which DMARDs you take. Every 4 to 12 weeks, for instance, most people taking methotrexate need blood tests, tests to check kidney and liver functions, and blood counts.

    Also keep doing the things you need to stay safe:

    * Keep up with vaccinations

    * Be sure to follow your doctor's advice about alcohol. Drinking more than recommended could be dangerous and lead to liver damage.

    Changes in Symptoms

    Sometimes a DMARD that has been reducing your symptoms starts to be less effective. If your symptoms are getting worse, call your doctor.

    The good news is that you still have many med options. Your doctor may adjust your dosage or add a different medication. It may take some time, but you and your doctor will find another approach that helps.

    WebMD Medical Reference

    Today on WebMD

    pain in brain and nerves
    Top causes and how to find relief.
    knee exercise
    8 exercises for less knee pain.
     
    acupuncture needles in woman's back
    How it helps arthritis, migraines, and dental pain.
    chronic pain
    Get personalized tips to reduce discomfort.
     
    illustration of nerves in hand
    Slideshow
    lumbar spine
    Slideshow
     
    Woman opening window
    Slideshow
    Man holding handful of pills
    Video
     
    Woman shopping for vegetables
    Slideshow
    Sore feet with high heel shoes
    Slideshow
     
    acupuncture needles in woman's back
    Slideshow
    man with a migraine
    Slideshow