Parkinson's disease mostly affects older people but can also occur in younger adults. The symptoms are the result of the gradual degeneration of nerve cells in the portion of the midbrain that controls body movements. The first signs are likely to be barely noticeable -- a feeling of weakness or stiffness in one limb, or a fine trembling of one hand when it is at rest. Eventually, the shaking (tremor) worsens and spreads, muscles become stiffer, movements slow down, and balance and coordination...
Levodopa is thought to be the most effective drug for controlling symptoms. But many doctors prescribe dopamine agonists in the beginning of the disease. This is because after a few years, levodopa can cause motor complications (times when the medicine suddenly stops working or when you have uncontrollable jerking movements). Talk to your doctor about which medicines are best for you.
Increasing, decreasing, or stopping the medicines you are taking may cause big changes in your symptoms and can be dangerous. Even if a medicine doesn't seem to be working, when you stop taking it, your symptoms of Parkinson's disease may be worse.
Taking medicine with food
Early in the disease, it might be helpful to take pills with food to help with nausea, which may be caused by some of the medicines for Parkinson's disease.
Later in the disease, taking the medicines at least 1 hour before meals (and at least 2 hours after meals) may help them work best.
Some medicines for Parkinson's disease don't work as well if you take them at the same time you eat food with protein in it, such as meat or cheese. The protein can block the medicine and keep it from working as well as it should.
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WebMD Medical Reference from Healthwise
April 18, 2014
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