For Adults with Chronic Moderate to Severe Plaque Psoriasis Who Are Candidates for Systemic or Phototherapy.
Payment Assistance
Finding a treatment that works for you can be difficult, but paying for it shouldn't be. ENBREL Support™ offers many financial support options for eligible patients.
Are You Eligible for Insurance Assistance? Specialists Can Help You Find Out
Insurance specialists are available at 1-888-4ENBREL (1-888-436-2735) Monday through Friday, 8 AM to 8 PM Eastern time, to help you find out if your insurance covers Enbrel® (etanercept) and if so, what your co-pay will be before you begin treatment. Or click here to verify insurance coverage.
We Offer Help with
Out-of-Pocket Costs for Eligible Patients
For all eligible patients,* the ENBREL Support™ card program may offer:
- First 6 months at no out-of-pocket cost to you
- After 6 months, $10 or less out-of-pocket per month †
- Support for your ENBREL co-pay or co-insurance, and prescription deductible
Program provides up to $4,000 of assistance per patient for each 6-month period.‡ Patient is responsible for costs above these amounts.
* Eligibility Criteria: Open to patients with commercial prescription insurance. Not open to uninsured patients or patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare including Medicare Part D, Medicaid, etc.) or where prohibited by law. Restrictions, including monthly maximums, may apply. Offer subject to change or discontinuation without notice. This is not health insurance. † Each time you fill your ENBREL prescription, you will receive 50% off your out-of-pocket costs or pay no more than $10 per month — whichever helps you more. ‡ For patients with moderate to severe plaque psoriasis, who are first starting ENBREL and prescribed 50-mg twice-weekly dosing, program provides an additional $2,000 per patient for the first 3 months of therapy only.Whatever Your Financial Situation,
We May Be Able to Help
Unemployed (with insurance)
If you lose your job — and are covered by any private insurance, including COBRA — eligible patients* can call to receive up to an additional 6 months of ENBREL at no co-pay cost to you.
No Insurance
ENcourage Foundation® is a patient assistance program supported by Amgen and Pfizer that provides ENBREL at no cost to patients who qualify and who have no or limited drug coverage. For more information, visit ENcourage Foundation.com.
Insured (but need more financial assistance)
If you have government insurance (such as Medicare Part D) or you need more financial assistance, we can refer you to independent foundations that may be able to help.
Please see Prescribing Information, Important Safety Information, and Medication Guide for complete details about ENBREL.
Prescription ENBREL is given by injection
Important Safety Information
What is the most important information I should know about Enbrel® (etanercept)?
ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your doctor should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.
There have been some cases of unusual cancers reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA or psoriasis may be more likely to get lymphoma.
Before starting ENBREL, tell your doctor if you:
- Have any existing medical conditions
- Are taking any medicines, including herbals
- Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your doctor says it is okay
- Have any open cuts or sores
- Have diabetes, HIV, or a weak immune system
- Have TB or have been in close contact with someone who has had TB
- Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your doctor if you are not sure
- Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don't know if these infections are common in the areas you've been to, ask your doctor
- Have or have had hepatitis B
- Have or have had heart failure
- Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
- Use the medicine Kineret® (anakinra), Orencia® (abatacept), or Cytoxan® (cyclophosphamide)
- Are taking anti-diabetic medicines
- Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
- Are scheduled to have surgery
- Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines.
- Are allergic to rubber or latex
- Are pregnant, planning to become pregnant, or breastfeeding
- Have been around someone with chicken pox
What are the possible side effects of ENBREL?
ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.
Common side effects include: Injection site reactions, upper respiratory infections (sinus infections), and headache.
These are not all the side effects with ENBREL. Tell your doctor about any side effect that bothers you or does not go away.
If you have any questions about this information, be sure to discuss them with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please see Prescribing Information and Medication Guide.
INDICATION
Moderate to Severe Plaque Psoriasis
ENBREL is indicated for the treatment of adult patients (18 years or older) with chronic moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
Supportive data
Moderate to Severe Plaque Psoriasis
- In medical studies, nearly half of patients saw 75% skin clearance in 3 months. Overall, 3 out of 4 patients saw 50% skin clearance in 3 months.
©2013 Amgen Inc., Thousand Oaks, CA 91320 and Pfizer Inc. All rights reserved. 63059-R4-V1
Manufactured by Immunex Corporation, Thousand Oaks, CA 91320. Marketed by Amgen Inc. and Pfizer Inc.
WebMD does not endorse any specific product, service, or treatment.
Safety Considerations
Safety information about Enbrel® (etanercept)
Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Patients treated with ENBREL also may be at risk for other serious side effects including nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; rare reports of serious blood problems (some fatal); heart failure, including new heart failure or worsening of heart failure you already have; new or worsening psoriasis; allergic reactions; immune reactions, including a lupus-like syndrome, lymphoma (a type of cancer) and other cancers. Call your doctor right away if you develop any of these. To see the full ENBREL Safety Information, click here.
Get a Closer Look at how ENBREL Works
Watch this short video, in which Dr. Craig Leonardi explains how plaque psoriasis is a disease of the immune system and describes how ENBREL works. See how ENBREL targets the immune system to reduce the overproduction of skin cells to help you get clearer skin.

