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For Adults with Chronic Moderate to Severe Plaque Psoriasis Who Are Candidates for Systemic or Phototherapy.

Talk with Your Doctor about Plaque Psoriasis

It is important to find a doctor who focuses on treating patients with psoriasis and to have a thorough discussion about your symptoms and treatment options. Family doctors and primary care physicians may not be trained specifically to treat plaque psoriasis, and even some dermatologists may not regularly treat plaque psoriasis.

Find a Dermatologist

A dermatologist treats a wide range of skin conditions. That's why it's important to find a dermatologist who focuses on treating patients with plaque psoriasis. Before you make an appointment, you may want to ask whether the doctor regularly treats patients with plaque psoriasis and if he or she:

  • Treats psoriasis as a disease of the immune system, not just a skin disease
  • Realizes that psoriasis can have an impact on your day-to-day routine
  • Believes that itching, flakes, and pain can be managed
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"When I saw results, I wanted to keep going back to my dermatologist. Sometimes, I just stop by to say hello." Gilbert H., moderate to severe plaque psoriasis patient and ENBREL user

Get an Accurate Diagnosis

An accurate diagnosis is a key first step in determining whether you have moderate to severe plaque psoriasis, are a candidate for systemic therapy or phototherapy, and exploring whether ENBREL may be right for you.

If you ever experience joint pain, swelling, and morning stiffness in addition to your psoriasis symptoms, tell your doctor about these symptoms. It may be psoriatic arthritis. Learn more about psoriatic arthritis.

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Take an Active Role

Taking an active role in your health care is important. It's best to ask questions if your doctor's answers or instructions are unclear. Bring up concerns even if your doctor doesn't ask.

It's important to talk to your doctor about how plaque psoriasis makes you feel — on the inside as well as the outside. The next time you visit with your doctor, make sure you share examples of how your plaque psoriasis affects you in social situations and at home.

  • Does your plaque psoriasis interfere with your everyday activities?
  • Does plaque psoriasis make social situations more difficult?
  • Does your plaque psoriasis make you feel self-conscious or withdrawn?
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Ask Helpful Questions

Asking questions about your plaque psoriasis and potential treatments may help with your treatment plan. The ENBREL team has created a list of questions to take with you to your dermatologist to discuss your plaque psoriasis and the possible treatments. Download Questions for Your Doctor

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Please see Prescribing Information, Important Safety Information, and Medication Guide for complete details about ENBREL.

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With ENBREL Support™, Help is Available to You

Access a variety of resources at no cost, including registered nurses and insurance specialists.

ENROLL TODAY

Prescription ENBREL is given by injection

Important Safety Information

What is the most important information I should know about Enbrel® (etanercept)?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your doctor should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.

There have been some cases of unusual cancers reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA or psoriasis may be more likely to get lymphoma.

Before starting ENBREL, tell your doctor if you:

  • Have any existing medical conditions
  • Are taking any medicines, including herbals
  • Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your doctor says it is okay
  • Have any open cuts or sores
  • Have diabetes, HIV, or a weak immune system
  • Have TB or have been in close contact with someone who has had TB
  • Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your doctor if you are not sure
  • Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don't know if these infections are common in the areas you've been to, ask your doctor
  • Have or have had hepatitis B
  • Have or have had heart failure
  • Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
  • Use the medicine Kineret® (anakinra), Orencia® (abatacept), or Cytoxan® (cyclophosphamide)
  • Are taking anti-diabetic medicines
  • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
  • Are scheduled to have surgery
  • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines.
  • Are allergic to rubber or latex
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have been around someone with chicken pox

What are the possible side effects of ENBREL?

ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.

Common side effects include: Injection site reactions, upper respiratory infections (sinus infections), and headache.

These are not all the side effects with ENBREL. Tell your doctor about any side effect that bothers you or does not go away.

If you have any questions about this information, be sure to discuss them with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Prescribing Information and Medication Guide.

INDICATION

Moderate to Severe Plaque Psoriasis

ENBREL is indicated for the treatment of adult patients (18 years or older) with chronic moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

Supportive data

Moderate to Severe Plaque Psoriasis

  • In medical studies, nearly half of patients saw 75% skin clearance in 3 months. Overall, 3 out of 4 patients saw 50% skin clearance in 3 months.
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Safety Considerations

Safety information about Enbrel® (etanercept)

Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Patients treated with ENBREL also may be at risk for other serious side effects including nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; rare reports of serious blood problems (some fatal); heart failure, including new heart failure or worsening of heart failure you already have; new or worsening psoriasis; allergic reactions; immune reactions, including a lupus-like syndrome, lymphoma (a type of cancer) and other cancers. Call your doctor right away if you develop any of these. To see the full ENBREL Safety Information, click here.

Get a Closer Look at how ENBREL Works

Watch this short video, in which Dr. Craig Leonardi explains how plaque psoriasis is a disease of the immune system and describes how ENBREL works. See how ENBREL targets the immune system to reduce the overproduction of skin cells to help you get clearer skin.

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