Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®): Complementary and alternative medicine - Patient Information [NCI] - Evaluation of CAM Approaches
It is important that the same rigorous scientific evaluation used to assess conventional approaches be used to evaluate CAM therapies. The National Cancer Institute (NCI) and the National Center for Complementary and Alternative Medicine (NCCAM) are sponsoring a number of clinical trials (research studies) at medical centers to evaluate CAM therapies for cancer. Conventional approaches to cancer treatment have generally been studied for safety and effectiveness through a rigorous scientific process that includes clinical trials with large numbers of patients. Less is known about the safety and effectiveness of complementary and alternative methods. Few CAM therapies have undergone rigorous evaluation. A small number of CAM therapies originally considered to be purely alternative approaches are finding a place in cancer treatment—not as cures, but as complementary therapies that may help patients feel better and recover faster. One example is acupuncture. According to a panel of
Genetics of Prostate Cancer (PDQ®): Genetics - Health Professional Information [NCI] - Psychosocial Issues in Prostate Cancer
Introduction Research to date has included survey,focus group,and correlation studies on psychosocial issues related to prostate cancer risk. (Refer to the PDQ summary on Elements of Cancer Genetics Risk Assessment and Counseling for further information on psychological issues related to genetic counseling for cancer risk assessment.) Genetic testing for prostate cancer susceptibility genes,...
Prostate Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Evidence of Benefit
Prior to the 1990s,the digital rectal examination (DRE) was the test traditionally mentioned for prostate cancer screening. Two other test procedures are also available: transrectal ultrasound (TRUS) imaging and serum prostate-specific antigen (PSA) concentrations.[ 1 ] Prostate cancer screening is controversial because of the lack of definitive evidence of benefit. A small randomized trial in .
Prostate Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Changes to This Summary (04 / 05 / 2013)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.SignificanceUpdated statistics with estimated new cases and deaths for 2013 (cited American Cancer Society as reference 1).Revised text to state that from 2005 to 2009 the overall age-adjusted incidence rate was 236 per 100,000 for African American men and 146.9 per 100,000 for white men (cited Howlader et al. as reference 10).Revised text to state that cancer statistics from the American Cancer Society and the National Cancer Institute indicated that between 2002 and 2008 the proportion of disease diagnosed at a locoregional stage and at a distant stage was 93% and 4% for whites, compared with 91% and 6% for African Americans, respectively.This summary is written and maintained by the PDQ Screening and Prevention Editorial Board, which is editorially independent of NCI. The summary reflects an
Prostate Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062910-nci-header
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Prostate Cancer Treatment
Genetics of Prostate Cancer (PDQ®): Genetics - Health Professional Information [NCI] - Polymorphisms and Prostate Cancer Susceptibility
The advent of large-scale high-throughput genotyping capabilities has resulted in an explosion of association studies between particular genes or genomic regions and prostate cancer risk. It is difficult to assess the import of any individual study. Accordingly,this PDQ Genetics of Prostate Cancer information summary will not attempt to provide an encyclopedic review of all such studies. ...
Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®): Complementary and alternative medicine - Health Professional Information [NCI] - Pomegranate
OverviewThis section contains the following key information:The pomegranate (Punica granatum L.) is native to Asia and cultivated widely throughout world.Various components of the pomegranate fruit contain bioactive compounds, including phenolics, flavonoids, and anthocyanins, some of which have antioxidant activity.Pomegranate juice and extract, as well as some of their bioactive components, inhibit the proliferation of various prostate cancer cell lines in vitro and induce apoptotic cell death in a dose-dependent manner.Cytochrome P450 enzyme inhibition and effects on insulin-like growth factor binding protein -3 (IGFBP-3) have been identified as being involved in the in vitro anticancer activity.Studies in rodent models of prostate cancer have shown that ingestion of pomegranate juice can decrease the rate of development, growth, and spread of prostate cancer.The only fully reported clinical trial of the use of pomegranate juice in men with prostate cancer showed that,
Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®): Complementary and alternative medicine - Patient Information [NCI] - Questions and Answers About Modified Citrus Pectin
What is modified citrus pectin?Pectin is a type of polysaccharide (a carbohydrate with many small sugar molecules that are chemically linked). Pectin is found in the cell walls of most plants and has gel-like qualities that are useful in making many types of food and medicine.Citrus pectin is found in the peel and pulp of citrus fruits such as oranges, grapefruit, lemons, and limes. Citrus pectin can be modified with high pH and heat to break its molecules into smaller pieces. Modified citrus pectin (also called MCP) can be digested and absorbed by the body. How is MCP administered or consumed? MCP may be taken by mouth in powder or capsule form. Have any preclinical (laboratory or animal) studies been conducted using MCP? A study in prostate cancer cells compared 3 different kinds of pectin: citrus pectin, PectaSol (a dietary supplement with MCP), and fractionated pectin powder. Prostate cancer cells treated with the pectin powder had more damage than those treated with citrus pectin
Prostate Cancer Screening (PDQ®): Screening - Patient Information [NCI] - What is screening?
Screening is looking for cancer before a person has any symptoms. This can help find cancer at an early stage. When abnormal tissue or cancer is found early,it may be easier to treat. By the time symptoms appear,cancer may have begun to spread. Scientists are trying to better understand which people are more likely to get certain types of cancer. They also study the things we do and the ...
Prostate Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Questions or Comments About This Summary
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