Pesticides Tied to Prostate Cancer
Routine Pesticide Use May Raise Prostate Cancer Risk
WebMD News Archive
Aug. 20, 2003 -- Men who routinely work with pesticides may
have a slightly higher risk of prostate cancer than others.
New research shows men whose jobs expose them to high levels of
pesticides have a 13% higher risk of prostate cancer than whose with low levels
of pesticide use.
The findings are based on a re-analysis of 22 studies on
pesticide use and prostate cancer risk published between 1995 and 2001.
The researchers were unable to confirm that the actual
pesticide exposure was what led to the increased prostate cancer risk. However,
the increase in prostate cancer found by pooling the studies together may have
important public health implications, they say.
Pesticides and the Prostate
Researcher G. Van Maele-Fabry of Ghent University in Belgium
and colleagues say one problem with many of the individual studies on pesticide
use and prostate cancer risk is that they did not take into consideration other
factors that affect prostate cancer risk such as ethnic origin and family
history of the disease.
In addition, the causes of prostate cancer are not precisely
known, which makes drawing any conclusions about the link between pesticide use
and prostate cancer risk difficult.
The study, published in the journal Occupational and
Environmental Medicine, shows the risk of prostate cancer was higher among
pesticide applicators than farmers and other occupations that involve pesticide
Previous research suggests that farmers may have a lower
prostate cancer risk due to lower prevalence of smoking, lower alcohol use,
dietary habits, and higher levels of physical activity.
The study shows the pooled prostate cancer risk estimates from
North American studies were higher than those conducted in Europe. But overall
pesticide use does not differ much between the two regions.
Researchers say that suggests that pesticide use may interact
with American lifestyle factors, such as high-fat diets and high rates of
obesity, to increase the risk of prostate cancer.
Although the findings aren't conclusive, researchers say they
once again stress the need to limit exposure to pesticides, and future studies
should focus on finding more reliable ways to estimate actual pesticide