Prostate Cancer Health Center
This article is from the WebMD News Archive
Broccoli May Help Cut Prostate Cancer
July 24, 2007 -- Men who often eat broccoli and cauliflower may be less likely to develop aggressive prostate cancer than men who skimp on those vegetables.
That news appears in the Journal of the National Cancer Institute.
The finding comes from a study of more than 29,000 U.S. men aged 55-74 who were followed for an average of four years.
When the study started, the men didn't have prostate cancer. They completed surveys about the foods they typically ate.
During the study, the men were regularly screened for prostate cancer. A total of 1,338 men were diagnosed with prostate cancer, including 520 men with aggressive prostate cancer.
The men who reported frequently eating cruciferous vegetables -- which include broccoli, cauliflower, cabbage, Brussels sprouts, mustard greens, and turnip greens -- were 40% less likely to be diagnosed with aggressive prostate cancer during the study than men who rarely ate those vegetables.
Cauliflower vs. Prostate Cancer?
Overall, the men's reported consumption of fruits and vegetables didn't appear to affect their chances of developing aggressive prostate cancer or less-aggressive prostate cancer.
But cruciferous vegetables were an exception.
Eating lots of cruciferous vegetables was linked to a lesser likelihood of being diagnosed with aggressive prostate cancer. Broccoli and cauliflower were the standout vegetables.
Men who reported eating cauliflower more than once per week were 52% less likely to be diagnosed with aggressive prostate cancer than men who reported eating cauliflower less than once a month.
Men who reported eating broccoli more than once per week were 45% less likely to be diagnosed with aggressive prostate cancer than men who reported eating broccoli less than once a month.
What's so special about cruciferous vegetables? They're rich in compounds that may help protect cells from DNA damage, note the researchers, who included Victoria Kirsh, PhD, of Cancer Care Ontario in Toronto.
Prostate Cancer Diet: No Promises
The researchers aren't promising men that eating those vegetables prevents aggressive prostate cancer. Scientists don't yet have a diet guaranteed to prevent prostate cancer.
However, there's no reason not to eat a diet rich in vegetables, as many health experts have long recommended.
The men in Kirsh's study weren't assigned to change their diets to directly test cruciferous vegetables against aggressive prostate cancer.
Kirsh's team considered many prostate cancer risk factors when they analyzed the data. But the researchers couldn't control for every possible influence. In addition, some men may have misreported their vegetable intake.
- Does your family have a history of prostate cancer? Discuss the risk factors and what you can do on WebMD's Prostate Cancer Support Group message board.
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL full prescribing information.


