Finding the Right Prostate Cancer Diet
Studies Point to Protective Role of Vegetables, Risky Role of Eggs
WebMD News Archive
Feb. 15, 2008 (San Francisco) -- Men: Take off the skin!
That's the advice of U.S. researchers who found that poultry and eggs double
the risk of prostate cancer progression.
"But when we broke it down, the increased risk was confined to poultry
with the skin on and eggs," says June M. Chan, ScD, of the University of
California, San Francisco.
The study of about 1,250 men treated for prostate cancer also showed
that orange and yellow vegetables, such as squash, yams, and carrots, and
cruciferous vegetables, such as broccoli, cut the risk of recurrence by about
Fruit and fish did not appear to help prevent prostate cancer from
returning, Chan tells WebMD.
The study results were based on data from CaPSURE, a national registry of
men with prostate cancer.
Though the findings need to be confirmed in other studies, Chan says that
they held up even after the researchers took into account other factors -- such
as age, weight, and exercise -- that can affect prostate cancer risks.
"If you eat chicken or poultry, eat it without the skin," she
Pomegranate Juice Protective
The study was presented at the Genitourinary Cancers Symposium, presented by
the American Society of Clinical Oncology (ASCO) and two other cancer care
Other research reported at the meeting pointed to the benefits of
pomegranate juice and lycopene in preventing prostate cancer progression.
Five years into a study testing the benefits of pomegranate juice, UCLA
researchers report that an 8-ounce glass a day continues to keep prostate
cancer recurrence away.
UCLA researcher Allan Pantuck, MD, and colleagues enrolled 46 men in a study
funded by the owners of POM Wonderful Co., the maker of the pomegranate juice
used in the study. The men all had rising PSA (prostate-specific antigen)
levels after cancer treatment; all drank 8 ounces of pomegranate juice every
As a measure of progression, the researchers looked at the time it took PSA
levels to double. The faster PSA levels double, the sooner a man is likely to
see prostate cancer return.
Original results of the study, published in 2006, showed that the men's
overall PSA doubling time was nearly four times slower after they began
drinking pomegranate juice.
Pantuck says that when the study was scheduled to end, a lot of the men
didn't want to give up the pomegranate juice. So its design was amended and men
were allowed to continue consuming their purple drink.
As of August 2007, 17 men had been followed for an average of 58 months.
Their PSA doubling time is now nearly five times slower than before they
started drinking the juice, Pantuck tells WebMD.
"There's a very durable improvement," he says.
The researchers are now enrolling men in a major clinical trial that will
pit pomegranate juice against placebo.