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PSA Test Has Shortcomings, Study Shows

Value of Prostate Cancer Test Has Eroded Over the Years, Researchers Say; More Biopsies on the Horizon?

Should We Biopsy Everyone? continued...

Vickers says PSA may be a useful test in young men, to identify those who might benefit from aggressive screening.

"In this study, 50% of the advanced cancers were diagnosed in men in the top 10% of PSA levels in that early screening, and two-thirds of the advanced cancers were seen in the 20% of men with the highest PSAs," he tells WebMD. "This shows that a single PSA prior to age 50 can predict extremely well who will eventually have advanced prostate cancer."

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