Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Font Size

Prostate Cancer Therapy May Not Help

Hormone Therapy Doesn't Increase Survival in Older Men With Early Prostate Cancer


Lu-Yao and Brawley suggest that these older men would have done just as well if their cancers had never been detected. Brawley notes that many of these men likely underwent continued prostate cancer screening with PSA tests. Others probably had possible prostate abnormalities detected by a urologist.

Regardless of how they got there, all these older men must have agreed to undergo prostate biopsies. And that may not have been the result of a fully informed decision, says Simon Hall, MD, head of urology at New York's Mount Sinai School of Medicine.

"You have to have a discussion with an older man before he has a prostate biopsy. You have to ask, 'Do you really want to open Pandora's Box?'" Hall tells WebMD. "Most patients with localized prostate cancer are not going to die from their disease in the first 10 years anyway. It is a legitimate question whether to screen patients this old, and whether urologists should biopsy older patients based on just a knee-jerk reaction."

Hall says there are very few men he would treat with hormone therapy alone.

"A lot of these older men are at low risk and don't need any treatment at all," he says. "It doesn't seem hormone therapy would make a difference, so why put them through the significant side effects and the cost?"

All of the experts who spoke with WebMD noted that the current study findings do not apply to younger men who might receive androgen-deprivation therapy in combination with surgery or radiation. Such men may benefit from hormone therapy.

Lu-Yao and colleagues report their findings in the July 9 issue of The Journal of the American Medical Association.

1 | 2

Today on WebMD

man with doctor
Symptoms, risks, treatments
man coughing
Men shouldn’t ignore
prostate cancer cells
What does this diagnosis mean?
doctor and male patient
Is it worth it?
cancer fighting foods
15 Cancer Symptoms Men Ignore
Prostate Enlarged
Picture Of The Prostate
Prostate Cancer Quiz
screening tests for men
Prostate Cancer Symptoms
Vitamin D