Prostate Cancer Health Center
Pomegranate Juice May Slow Prostate Cancer
April 26, 2009 -- Drinking 8 ounces of pomegranate juice daily may slow the progression of localized prostate cancer ( prostate cancer that hasn't spread), a new study shows.
The study included 48 men who had surgery or radiation therapy to treat localized prostate cancer.
When the study started in 2003, the men's PSA levels were doubling every 15 months. In prostate cancer patients, PSA (prostate specific antigen) is used to monitor their cancer.
All of the men drank 8 ounces of pomegranate juice daily, and that slowed down the time it took for their PSA levels to double, as the researchers reported in 2006.
After that, the researchers -- who included Stanford University urologist Allan Pantuck, MD -- kept following the patients every three months. Fifteen of the patients stayed with the study for up to 64 months (a little more than five years), and it typically took four times longer for their PSA levels to double when they were drinking pomegranate juice, compared to their PSA doubling time at the study's start.
The results were presented at the American Urological Association's 104th annual scientific meeting in Chicago.
Five of the six researchers who conducted the study disclose ties to POM Wonderful, which makes the pomegranate juice used in the study.
In 2007, another team of researchers bought pomegranates, made their own pomegranate juice, and tested it against human prostate cancer cells grafted into mice. Those tumors grew slower than other tumors treated with a placebo solution.
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Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL full prescribing information.
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