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Common Prostate Cancer Treatment May Be Less Risky Than Thought

But Concerns About ADT Treatment Remain for Heart Patients

Tomaselli: Men With Heart Disease Should Be Followed Closely

The researchers add that the treatment-related risk isn’t clear for men with known heart disease or those who have had a heart attack.

American Heart Association President Gordon Tomaselli, MD, tells WebMD that the research as a whole emphasizes the importance of individualizing decisions about the use of ADT.

He adds that if the risk-benefit analysis favors using the treatment in patients with heart disease and stroke risk, these patients need to be followed very carefully to ensure that modifiable risk factors for heart attack and stroke, such as high blood pressure and cholesterol, are treated aggressively.

American Cancer Society Chief Medical Officer Otis Brawley, MD, says the most recent data on ADT treatment suggest that concerns about its use in men with existing heart disease are well warranted.

“About a third of men in the U.S. who are diagnosed with prostate cancer have a stroke at some point in their lives,” he tells WebMD. “There is an appropriate use for these treatments and an inappropriate use for them and I would be leery of using them in men who would not have qualified for these studies.”

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