Drug for Enlarged Prostate May Slow Cancer Growth
Could Avodart Be an Alternative to Surgery, Radiation for Low-Risk Prostate Cancer?
‘More Study Needed to Prove Benefit’
Fleshner says the fact that significantly fewer men who took Avodart chose to have surgery or radiation shows a "real world" benefit for the treatment.
But Brooks says the study was not large enough or the follow-up long enough to prove that the drug improves long-term outcomes in patients with low-risk prostate cancers.
He agrees that drug treatments that clearly affect disease progression could convince more low-risk patients to forgo surgery or radiation.
“Unfortunately, I don’t think we can put this drug in that category yet,” he tells WebMD.
“With or without a drug treatment, we now know that active surveillance is a reasonable approach for many men with low-risk prostate cancers,” Brooks says.
“We now have relatively well-defined criteria to tell us when active surveillance is appropriate and reasonable protocols to help us follow men who choose this path.”