Early Baldness in Black Men: Prostate Cancer Link?
Hair loss by age 30 may raise risk, study suggests
WebMD News Archive
This year, the American Cancer Society predicts about 238,000 new cases of prostate cancer will be diagnosed and that more than 29,000 men will die of the cancer.
Besides race, known risk factors for prostate cancer include older age and a family history of the disease.
Zeigler-Johnson isn't sure how to explain the association between prostate cancer and baldness, but said male hormones might play a role. "Perhaps it is related to androgens, in particular to dihydrotestosterone [DHT], a metabolite of testosterone," she said.
"We know an increase in DHT increases prostate cancer occurrence and progression," she said. "But it is also related to thinning of the hair follicles." That thinning makes it difficult for hair to survive.
Dr. Otis Brawley, chief medical officer of the American Cancer Society, said the study provides "more evidence of a link that has been talked about since the '70s."
The finding about balding in younger men is the newest information, he said.
Another expert, Dr. Lionel Banez, a research investigator at Durham Veterans Affairs Medical Center in Durham, N.C., said the new findings are important "because this is the largest cohort of purely African-American men published which examines the link between baldness and prostate cancer."
However, it is "quite premature" to use the findings to make any clinical recommendations about screening for the cancer, he said.
If other research confirms the link, Zeigler-Johnson said doctors might decide to follow and screen balding men more closely for prostate cancer.
One screening test for prostate cancer is the PSA (prostate-specific antigen) blood test, which measures normal and cancerous cells in the prostate gland. When PSA levels are high, it sometimes indicates cancer.
"We still do not know if prostate cancer screening saves lives," said Brawley. Currently, the American Cancer Society recommends informing men of average risk, without symptoms, of the known pitfalls (such as false "positive" results) and potential benefits (early detection) of prostate cancer screening beginning at age 50. They then can make a decision about screening.