RA Support Center

Ready, Set, Rituxan: What to Expect from Therapy

Taking Rituxan may be a change from other treatments you've tried in the past. For Rituxan to work, it must enter your bloodstream directly through an intravenous (IV) infusion. One course of treatment with Rituxan requires 2 separate IV infusions given 2 weeks apart.

Today and through 6 Months Away

After treatment with Rituxan, you may experience improvement in your rheumatoid arthritis (RA) through 6 months. That could mean 6 months of less swelling in the morning, or less joint pain during your daily routine.

Because RA is a chronic condition, you will eventually have to be treated again. You and your doctor should discuss when your next course of treatment is needed.

Your First Infusion

If you've never had an infusion before, there are a few things you should know. First, your doctor's office will schedule appointments for your first course of Rituxan. Treatment may take place at your doctor's office, an infusion center, or a hospital.

You may be given additional medicine before each infusion to make you more comfortable. Let your healthcare professional know if you experience any side effects during the infusion.

Each infusion could take 4 to 6 hours, so plan accordingly. Bring something to help pass the time, like a book or music. If the facility where you will be receiving the infusion allows it, consider bringing some food along in case you get hungry during the infusion.

If you experience any side effects after an infusion, seek immediate medical attention.

Your Second Infusion and Beyond

Your second infusion may take slightly less time than your first, but again, it will last several hours. If you didn't experience any side effects from your first infusion, your second may go just as smoothly. If you did, simply talk with your doctor about how best to proceed with treatment.